Lortab and Diprivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lortab (acetaminophen; hydrocodone bitartrate) and Diprivan (propofol). Common drug interactions include blood fibrinogen decreased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lortab and Diprivan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

On Aug, 04, 2026

18 people who take Lortab and Diprivan together, and have interactions are studied.

What are the common drug interactions of Lortab and Diprivan, by gender? *:

female:

Blood fibrinogen decreased
Blood triglycerides increased
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer in situ
Breast mass
Burning sensation
Cardiac failure congestive
Cardiac flutter (abnormal heart rhythm)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Anxiety
Cardiac failure congestive
Depression
Emotional distress
Fear
Ileus (a painful obstruction of the ileum or other part of the intestine)
Injury

What are the common drug interactions of Lortab and Diprivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Procedural vomiting
Sinusitis bacterial (bacterial infection of sinus)
Viral infection
Cough

20-29:

Abdominal distension
Aggression
Blood cholesterol increased
Bradyarrhythmia (heart slowness)
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac flutter (abnormal heart rhythm)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest tightness
Coma (state of unconsciousness lasting more than six hours)

30-39:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

40-49:

n/a

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Haemorrhoid operation
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypergammaglobulinaemia (elevated levels of gamma globulin)
Hypoxia (low oxygen in tissues)

60+:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Depression
Dyspnoea (difficult or laboured respiration)
Injury
Pulmonary hypertension (increase in blood pressure in the lung artery)
Urinary tract infection

What are the existing conditions these people have? *

Type 1 Diabetes: 3 people, 16.67%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 11.11%
Hypoglycemia (low blood sugar): 2 people, 11.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.11%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 2 people, 11.11%
Constipation: 2 people, 11.11%
Cystic Fibrosis (disease of the secretary glands): 2 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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