Lortab and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lortab (acetaminophen; hydrocodone bitartrate) and Pentoxifylline (pentoxifylline). Common drug interactions include upper respiratory tract infection among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Lortab and Pentoxifylline. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

On Jul, 15, 2026

37 people who take Lortab and Pentoxifylline together, and have interactions are studied.

Lortab and Pentoxifylline drug interactions.

What are the common drug interactions of Lortab and Pentoxifylline, by gender? *:

female:

Upper respiratory tract infection
Atypical mycobacterial infection (infections caused by several types of mycobacterium similar to the germ that causes tuberculosis)
Bacterial infection
Benign hepatic neoplasm (benign (non-cancerous) tumours of the liver)
Blood cholesterol increased
Cardiolipin antibody positive
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Furuncle (infection of the hair follicle)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)

male:

Anaemia (lack of blood)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Bone disorder
Bone fragmentation
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Bone swelling
Cardiac failure congestive
Cellulitis (infection under the skin)
Chest pain
Dental caries

What are the common drug interactions of Lortab and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Benign hepatic neoplasm (benign (non-cancerous) tumours of the liver)
Cardiolipin antibody positive
Chest pain
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Pain in extremity
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Anisocytosis (patient's red blood cells are of unequal size)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Blood cholesterol increased

50-59:

Decreased appetite
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fatigue (feeling of tiredness)
Furuncle (infection of the hair follicle)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Hot flushes (sudden feelings of heat)
Incision site infection (infection at incision site)
Ligament sprain (ligament stretched)
Mycobacterium marinum infection (a free-living bacterium, which causes opportunistic infections in humans)

60+:

Cellulitis (infection under the skin)
Anaemia (lack of blood)
Blood cholesterol increased
Bone disorder
Bone fragmentation
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Bone swelling
Cardiac failure congestive
Chest pain
Dental caries

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 48.65%
Trismus (reduced opening of the jaws): 16 people, 43.24%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
Polyp: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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