Losartan and Belbuca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Belbuca (buprenorphine hydrochloride). Common drug interactions include fatigue among females and therapeutic response decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Belbuca. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

What is Belbuca?

Belbuca has active ingredients of buprenorphine hydrochloride. eHealthMe is studying from 3,022 Belbuca users. Check the latest studies of Belbuca.



On Jul, 20, 2026

49 people who take Losartan and Belbuca together, and have interactions are studied.

Losartan and Belbuca drug interactions.

What are the common drug interactions of Losartan and Belbuca, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Neuropathy peripheral (surface nerve damage)
  3. Abdominal pain upper
  4. Asthenia (weakness)
  5. Pain
  6. Cataract (clouding of the lens inside the eye)
  7. Dental caries
  8. Depression
  9. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  10. Fall

male:

  1. Therapeutic response decreased (less preventive response)
  2. Back pain
  3. Pyrexia (fever)
  4. Vein disorder
  5. Abdominal discomfort
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Constipation
  9. Dizziness
  10. Drug ineffective

What are the common drug interactions of Losartan and Belbuca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dental caries
  2. Tooth discolouration (a change in colour of teeth)
  3. Tooth disorder (tooth disease)
  4. Tooth injury

40-49:

  1. Abdominal pain upper
  2. Knee arthroplasty

50-59:

  1. Pyrexia (fever)
  2. Chronic kidney disease
  3. Abdominal discomfort
  4. Abdominal pain upper
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Back pain
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Constipation
  10. Cough

60+:

  1. Therapeutic response decreased (less preventive response)
  2. Breakthrough pain
  3. Dizziness
  4. Dyspnoea (difficult or laboured respiration)
  5. Ear discomfort
  6. Headache (pain in head)
  7. Presyncope
  8. Secretion discharge
  9. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  10. Chills (felling of cold)

What are the existing conditions these people have? *

  1. Pain: 15 people, 30.61%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 20.41%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 10.20%
  4. High Blood Cholesterol: 5 people, 10.20%
  5. Depression: 5 people, 10.20%
  6. Diabetes: 4 people, 8.16%
  7. Asthma: 4 people, 8.16%
  8. Type 2 Diabetes: 3 people, 6.12%
  9. Sleep Disorder: 3 people, 6.12%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and Belbuca?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Losartan and Belbuca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Belbuca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Losartan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Belbuca and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and buprenorphine hydrochloride (the active ingredients of Losartan and Belbuca, respectively), and Losartan and Belbuca (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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