Losartan and Fetzima drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Fetzima (levomilnacipran hydrochloride). Common drug interactions include infusion site erythema among females and back disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Fetzima. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,695 Losartan users. Check the latest studies of Losartan.

What is Fetzima?

Fetzima has active ingredients of levomilnacipran hydrochloride. It is often used in depression. eHealthMe is studying from 2,077 Fetzima users. Check the latest studies of Fetzima.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

46 people who take Losartan and Fetzima together, and have interactions are studied.

What are the common drug interactions of Losartan and Fetzima, by gender? *:

female:

Infusion site erythema (reddening of the skin at infusion site)
Infusion site pruritus (severe itching at infusion site)
Infusion site swelling
Malaise (a feeling of general discomfort or uneasiness)
Middle ear effusion (fluid in middle ear)
Nephrogenic anaemia (anaemia due to kidney disease)
Neuropathy peripheral (surface nerve damage)
Organ failure
Oropharyngeal pain
Panic attack

male:

Back disorder
Rash
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Fatigue (feeling of tiredness)
Gait disturbance
Insomnia (sleeplessness)
Ligament sprain (ligament stretched)
Osteopenia (a condition where bone mineral density is lower than normal)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Losartan and Fetzima, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Back disorder
Rash
Road traffic accident
Anxiety
Neuralgia (pain in one or more nerves)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Accident at work
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Fatigue (feeling of tiredness)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Confusional state
Psoriasis (immune-mediated disease that affects the skin)
Vitamin d deficiency
Wound infection
Abnormal dreams
Arrhythmia (irregular heartbeat)
Agitation (state of anxiety or nervous excitement)
Anxiety

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 34.78%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 21.74%
Insomnia (sleeplessness): 7 people, 15.22%
Immunodeficiency Common Variable: 4 people, 8.70%
Stress And Anxiety: 3 people, 6.52%
Pain: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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