Losartan and Flector drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Losartan (losartan potassium) and Flector (diclofenac epolamine). Common drug interactions include gastric disorder among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Losartan and Flector. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.
What is Losartan?
Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.
What is Flector?
Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.
66 people who take Losartan and Flector together, and have interactions are studied.

What are the common drug interactions of Losartan and Flector, by gender? *:
female:
- Gastric disorder (disease of stomach)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hepatic steatosis (fatty liver disease)
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Injection site pain
- Joint dislocation (a joint position is changed from normal position)
- Local swelling (swelling at the site of some application of substance or injury)
- Pleural effusion (water on the lungs)
- Pneumonia
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Decreased activity
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Depression
- Diarrhoea
- Drug ineffective
- Emotional distress
- Fatigue (feeling of tiredness)
What are the common drug interactions of Losartan and Flector, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
40-49:
- Proteinuria (presence of protein in the urine)
- Renal impairment (severely reduced kidney function)
50-59:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Diarrhoea
- Chronic kidney disease
- Pancreatitis (inflammation of pancreas)
- Polymyalgia rheumatica (pain in many muscles)
- Renal impairment (severely reduced kidney function)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Fatigue (feeling of tiredness)
60+:
- Chronic kidney disease
- Dry mouth
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Aphonia (inability to produce voice)
- Arthralgia (joint pain)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Facial pain
- Fatigue (feeling of tiredness)
- Food intolerance (inability to have food)
What are the existing conditions these people have? *
- High Blood Cholesterol: 18 people, 27.27%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 19.70%
- Asthma: 9 people, 13.64%
- Depression: 8 people, 12.12%
- Stress And Anxiety: 6 people, 9.09%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 9.09%
- Diabetes: 6 people, 9.09%
- Rickets (softening of bones): 5 people, 7.58%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.58%
- Cardiac Disorder: 5 people, 7.58%
* Approximation only. Some reports may have incomplete information.
Do you take Losartan and Flector?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Losartan and Flector:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flector:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Losartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flector and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on losartan potassium and diclofenac epolamine (the active ingredients of Losartan and Flector, respectively), and Losartan and Flector (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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