Losartan and Fragmin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Fragmin (dalteparin sodium). Common drug interactions include hyperuricaemia among females and aplasia pure red cell among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Fragmin. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

What is Fragmin?

Fragmin has active ingredients of dalteparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 11,999 Fragmin users. Check the latest studies of Fragmin.



On Jul, 16, 2026

52 people who take Losartan and Fragmin together, and have interactions are studied.

Losartan and Fragmin drug interactions.

What are the common drug interactions of Losartan and Fragmin, by gender? *:

female:

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  2. Hypokalaemia (low potassium)
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Muscle spasms (muscle contraction)
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  7. Oxygen saturation decreased
  8. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  9. Postictal state
  10. Pulmonary congestion (congestion in the lungs)

male:

  1. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  2. Vomiting
  3. Nausea (feeling of having an urge to vomit)
  4. Pyramidal tract syndrome (disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord)
  5. Tendon rupture (tear of tendon)
  6. Truncus coeliacus thrombosis (blood clot in the mesenterial vein)
  7. Abdominal pain
  8. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  9. Angiopathy (generic term for a disease of the blood vessels)
  10. Arthralgia (joint pain)

What are the common drug interactions of Losartan and Fragmin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Weight increased
  2. Cardiac failure
  3. Cardiomegaly (increased size of heart than normal)
  4. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  5. Oxygen saturation decreased
  6. Pulmonary congestion (congestion in the lungs)
  7. Renal failure (kidney dysfunction)
  8. Urine output decreased

50-59:

  1. Diarrhoea
  2. Epistaxis (bleed from the nose)
  3. Platelet count decreased
  4. Blood creatinine increased
  5. Constipation
  6. Febrile neutropenia (fever with reduced white blood cells)
  7. Hyperkeratosis (thickening of the outer layer of the skin)
  8. Hypokalaemia (low potassium)
  9. Nausea (feeling of having an urge to vomit)
  10. Rash

60+:

  1. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  2. Dyspnoea (difficult or laboured respiration)
  3. Pyramidal tract syndrome (disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord)
  4. Pyrexia (fever)
  5. Tendon rupture (tear of tendon)
  6. Abdominal mass (localized enlargement or swelling in the human abdomen)
  7. Abdominal pain
  8. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  9. Adjustment disorder with depressed mood
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 21.15%
  2. High Blood Cholesterol: 5 people, 9.62%
  3. Nausea (feeling of having an urge to vomit): 4 people, 7.69%
  4. Muscle Spasms (muscle contraction): 4 people, 7.69%
  5. Joint Pain: 4 people, 7.69%
  6. Pain: 3 people, 5.77%
  7. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 5.77%
  8. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 5.77%
  9. Diarrhea: 3 people, 5.77%
  10. Diabetes: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and Fragmin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Losartan and Fragmin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fragmin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Losartan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fragmin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and dalteparin sodium (the active ingredients of Losartan and Fragmin, respectively), and Losartan and Fragmin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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