Losartan and Methylfolate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Methylfolate (folic acid). Common drug interactions include anxiety among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Methylfolate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Methylfolate?

Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

19 people who take Losartan and Methylfolate together, and have interactions are studied.

Losartan and Methylfolate drug interactions.

What are the common drug interactions of Losartan and Methylfolate, by gender? *:

female:

Anxiety
Chronic kidney disease
Depression
Gait disturbance
Pain in extremity
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Emotional distress

male:

Asthenia (weakness)
Eating disorder
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Dental caries
Depression
Device dislocation
Dysarthria (speech disorder)
Fall
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Losartan and Methylfolate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Depression
Emotional distress
Foot fracture
Gait disturbance
Heart rate increased
Multiple fractures
Osteoporosis (bones weak and more likely to break)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Balance disorder
Blood sodium decreased
Chest pain
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Dental caries

What are the existing conditions these people have? *

Indigestion: 3 people, 15.79%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.79%
Hiv Infection: 2 people, 10.53%
Blood Glucose Abnormal: 2 people, 10.53%
Diabetes: 2 people, 10.53%
Gastric Disorder (disease of stomach): 2 people, 10.53%
Gastric Ulcer (stomach ulcer): 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
Abdominal Discomfort: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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