Losartan and Mysoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Mysoline (primidone). Common drug interactions include suicidal ideation among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Mysoline. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,695 Losartan users. Check the latest studies of Losartan.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

52 people who take Losartan and Mysoline together, and have interactions are studied.

Losartan and Mysoline drug interactions.

What are the common drug interactions of Losartan and Mysoline, by gender? *:

female:

Suicidal ideation
Viith nerve paralysis
Visual impairment
Ataxia (loss of full control of bodily movements)
Anaemia (lack of blood)
Haematemesis (vomiting of blood)
Haematochezia (passage of stools containing blood)
Impaired gastric emptying
Delirium (wild excitement)
Embolism arterial (blood clot that has travelled through your arteries and become stuck)

male:

Chronic kidney disease
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cardiac failure congestive
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diarrhoea
Rectal haemorrhage (bleeding from anus)
Renal tubular necrosis (death of kidney tubules)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Losartan and Mysoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Depression
Fibromyalgia (a long-term condition which causes pain all over the body)
Otitis media (inflammation of the middle ear)
Lacrimation increased
Lagophthalmos (the inability to close the eyelids completely)
Myopia (difficult to see objects that are far away)
Visual acuity reduced (reduced clearness of vision)
Vaginal haemorrhage (vaginal bleeding)
Apnoea (suspension of external breathing)
Balance disorder

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Speech disorder
Stress

50-59:

Alopecia (absence of hair from areas of the body)
Haemoglobin decreased
Migraine (headache)
Restless legs syndrome (a powerful urge to move your legs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Suicidal ideation

60+:

Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Delirium (wild excitement)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Neuropathy peripheral (surface nerve damage)
Abdominal pain lower
Arthralgia (joint pain)
Back pain
Blood magnesium decreased
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 17.31%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.62%
Stress And Anxiety: 4 people, 7.69%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 7.69%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 5.77%
High Blood Cholesterol: 3 people, 5.77%
Diabetes: 3 people, 5.77%
Chest Pain: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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