Losartan and Nplate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Nplate (romiplostim). Common drug interactions include vaginal discharge among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Nplate. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

54 people who take Losartan and Nplate together, and have interactions are studied.

What are the common drug interactions of Losartan and Nplate, by gender? *:

female:

Vaginal discharge
Vaginal haemorrhage (vaginal bleeding)
Vitamin d deficiency
Death
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Ovarian cyst (fluid filled sac of the ovary)
Peripheral swelling
Platelet disorder
Bradycardia (abnormally slow heart action)

male:

Platelet count decreased
Therapeutic response decreased (less preventive response)
Anal candidiasis (rectal fungal infection)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Chest pain
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysphagia (a condition in which swallowing is difficult or painful)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Evans syndrome (autoimmune disorder in which the body makes antibodies that destroy the red blood cells, platelets)

What are the common drug interactions of Losartan and Nplate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Platelet count decreased
Platelet disorder
Gastritis (inflammation of stomach)
Osteoporosis (bones weak and more likely to break)
Thrombocytopenia (decrease of platelets in blood)
Thyroid cancer

50-59:

Haemorrhage (bleeding)
Headache (pain in head)
Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
Mean platelet volume increased (more than normal average size of platelet cells in blood)
Monocyte count decreased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephropathy (damage to or disease of a kidney)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral vascular disorder

60+:

Platelet count decreased
Thrombocytopenia (decrease of platelets in blood)
Hypoxia (low oxygen in tissues)
Marrow hyperplasia (increased bone marrow)
Oedema (fluid collection in tissue)
Oesophageal candidiasis (fungal infection of oesophagus)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Thrombocytopenic purpura (a bleeding disorder in which the immune system destroys platelets)
Drug ineffective

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 18 people, 33.33%
Pain: 4 people, 7.41%
Thrombocytopenia (decrease of platelets in blood): 3 people, 5.56%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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