Losartan and Sovaldi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Losartan (losartan potassium) and Sovaldi (sofosbuvir). Common drug interactions include vomiting among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Losartan and Sovaldi. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.
What is Losartan?
Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.
What is Sovaldi?
Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.
77 people who take Losartan and Sovaldi together, and have interactions are studied.

What are the common drug interactions of Losartan and Sovaldi, by gender? *:
female:
- Vomiting
- Chills (felling of cold)
- Constipation
- Dizziness
- Pain
- Rash
- Renal failure (kidney dysfunction)
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
male:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Depression
- Drug ineffective
- Gastrointestinal hypomotility (less activity of the intestinal tract)
- Hepatic failure (liver failure)
- Insomnia (sleeplessness)
- Death
- Weight decreased
- Asthenia (weakness)
What are the common drug interactions of Losartan and Sovaldi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia (lack of blood)
- Abdominal pain
- Asthenia (weakness)
- Nausea (feeling of having an urge to vomit)
- Colitis (inflammation of colon)
- Fatigue (feeling of tiredness)
- Pruritus (severe itching of the skin)
- Rash
50-59:
- Weight decreased
- Abdominal pain upper
- Acute myocardial infarction (acute heart attack)
- Anaemia (lack of blood)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Bone pain
- Cardiovascular disorder (heart diseases)
- Dysgeusia (disorder of the sense of taste)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Gout (uric acid crystals building up in the body)
60+:
- Vomiting
- Constipation
- Haemoglobin decreased
- Hepatic failure (liver failure)
- Gastrointestinal hypomotility (less activity of the intestinal tract)
- Insomnia (sleeplessness)
- Pyrexia (fever)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood bilirubin increased
What are the existing conditions these people have? *
- Hepatitis C: 50 people, 64.94%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.09%
- Diabetes: 5 people, 6.49%
- Muscle Spasms (muscle contraction): 4 people, 5.19%
- Hiv Infection: 4 people, 5.19%
* Approximation only. Some reports may have incomplete information.
Do you take Losartan and Sovaldi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Losartan and Sovaldi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sovaldi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Losartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sovaldi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on losartan potassium and sofosbuvir (the active ingredients of Losartan and Sovaldi, respectively), and Losartan and Sovaldi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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