Losartan and Videx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Videx (didanosine). Common drug interactions include pain in extremity among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Videx. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Videx?

Videx has active ingredients of didanosine. eHealthMe is studying from 7,927 Videx users. Check the latest studies of Videx.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

48 people who take Losartan and Videx together, and have interactions are studied.

What are the common drug interactions of Losartan and Videx, by gender? *:

female:

Pain in extremity
Peripheral swelling
Proteinuria (presence of protein in the urine)
Quality of life decreased
Renal pain (kidney pain)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tooth loss
Acidosis hyperchloraemic (increased acidity in the blood and other body tissue with decrease in plasma bicarbonate concentration)
Anaemia (lack of blood)
Atrioventricular block (heart block)

male:

Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Blood creatinine increased
Spinal compression fracture (fracture due to spinal compression on bone)
Fatigue (feeling of tiredness)
Quality of life decreased
Decreased activity
Drug resistance (reduction in effectiveness of a drug)
Back pain

What are the common drug interactions of Losartan and Videx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Blood creatinine increased
Bone density decreased
Depression
Disturbance in attention
Emotional distress
Fear
Osteopenia (a condition where bone mineral density is lower than normal)

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Decreased activity
Emotional distress
Fatigue (feeling of tiredness)
Loss of employment
Mobility decreased (ability to move is reduced)
Pain
Quality of life decreased

40-49:

Mobility decreased (ability to move is reduced)
Multiple fractures
Renal impairment (severely reduced kidney function)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Foot fracture
Acidosis hyperchloraemic (increased acidity in the blood and other body tissue with decrease in plasma bicarbonate concentration)
Asthenia (weakness)
Drug resistance (reduction in effectiveness of a drug)
Fall
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

50-59:

Emotional distress
Pain
Chronic kidney disease
Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

60+:

Chronic kidney disease
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Blood pressure fluctuation
Bone loss
Decreased appetite
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Hiv Infection: 47 people, 97.92%
Asthma: 8 people, 16.67%
Pain: 5 people, 10.42%
Hypersensitivity: 5 people, 10.42%
Depression: 5 people, 10.42%
Erection Problems: 4 people, 8.33%
Viral Infection: 3 people, 6.25%
Urinary Tract Infection Bacterial: 3 people, 6.25%
Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 6.25%
Laxative Supportive Care: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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