Lotrel and Biotin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotrel (amlodipine besylate; benazepril hydrochloride) and Biotin (biotin). Common drug interactions include rash among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Lotrel and Biotin. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

On Jul, 25, 2026

35 people who take Lotrel and Biotin together, and have interactions are studied.

What are the common drug interactions of Lotrel and Biotin, by gender? *:

female:

Rash
Renal failure (kidney dysfunction)
Asthenia (weakness)
Blood potassium increased
Chest pain
Drug ineffective
Gait disturbance
Insomnia (sleeplessness)
Knee arthroplasty
Malaise (a feeling of general discomfort or uneasiness)

male:

Constipation
Eye disorder
Rectal haemorrhage (bleeding from anus)

What are the common drug interactions of Lotrel and Biotin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Flushing (the warm, red condition of human skin)
Rash

40-49:

Urticaria (rash of round, red welts on the skin that itch intensely)
Vocal cord atrophy (decrease in size of vocal cord)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Urinary tract infection
Vomiting
Aortic disorder
Aphasia (damage to the parts of the brain that control language)
Biliary dilatation
Biliary fistula
Bladder dilatation

50-59:

Knee arthroplasty
Acute respiratory failure
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure decreased
Intervertebral disc protrusion (spinal disc protrusion)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pain
Pruritus (severe itching of the skin)

60+:

Arthralgia (joint pain)
Chronic kidney disease
Insomnia (sleeplessness)
Oedema peripheral (superficial swelling)
Pain in extremity
Pruritus (severe itching of the skin)
Skin lesion
Stomatitis (inflammation of mucous membrane of mouth)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Joint swelling

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.29%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 11.43%
Anaemia (lack of blood): 4 people, 11.43%
Sleep Disorder: 4 people, 11.43%
Skin Disorder (skin disease): 4 people, 11.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.43%
Pain: 4 people, 11.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.43%
Weakness: 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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