Lotrisone and Pepcid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotrisone (betamethasone dipropionate; clotrimazole) and Pepcid (famotidine). Common drug interactions include lymphadenopathy among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Lotrisone and Pepcid. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Lotrisone?

Lotrisone has active ingredients of betamethasone dipropionate; clotrimazole. eHealthMe is studying from 1,819 Lotrisone users. Check the latest studies of Lotrisone.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

On Jul, 19, 2026

68 people who take Lotrisone and Pepcid together, and have interactions are studied.

What are the common drug interactions of Lotrisone and Pepcid, by gender? *:

female:

Lymphadenopathy (disease or enlargement of lymph nodes)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Abdominal hernia
Breast cancer metastatic
Cough
Intervertebral disc protrusion (spinal disc protrusion)
Sinusitis (inflammation of sinus)
Tooth disorder (tooth disease)
Toothache (tooth pain)
Upper respiratory tract infection

male:

Pain
Renal failure (kidney dysfunction)
Nausea (feeling of having an urge to vomit)
Pneumonia
Scar
Urinary tract infection
Abdominal distension
Abdominal pain
Alexia
Anoxic encephalopathy (brain damage due to lack of oxygen)

What are the common drug interactions of Lotrisone and Pepcid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Postoperative wound infection

20-29:

Abdominal pain upper
Acute sinusitis
Agitation (state of anxiety or nervous excitement)
Anxiety
Arthropathy
Asthma
Back pain
Chest pain
Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
Confusional state

30-39:

Atelectasis (partial or complete collapse of the lung)
Drug ineffective
Vision blurred
Coma (state of unconsciousness lasting more than six hours)
Drug dependence
Injury
Oedema peripheral (superficial swelling)
Pyrexia (fever)
Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

40-49:

Fatigue (feeling of tiredness)
Abdominal hernia
Actinomycosis (infection that causes sores, or abscesses)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Balance disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain

50-59:

Atherosclerosis (disorder of the arteries)
Blood cholesterol increased
Blood pressure increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
Cardiac disorder
Cardiac failure congestive
Chest pain
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Constipation

60+:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cough
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Fatigue (feeling of tiredness)
Haemoglobin decreased
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Multi-organ failure (multisystem organ failure)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Pain: 19 people, 27.94%
Insomnia (sleeplessness): 10 people, 14.71%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 11.76%
Metastases To Bone (cancer spreads to bone): 7 people, 10.29%
Depression: 7 people, 10.29%
Rashes (redness): 6 people, 8.82%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 8.82%
Stress And Anxiety: 5 people, 7.35%
High Blood Pressure: 5 people, 7.35%
Fungal Infection: 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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