Lovenox and Optimark drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lovenox (enoxaparin sodium) and Optimark (gadoversetamide). Common drug interactions include joint stiffness among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Lovenox and Optimark. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Optimark?

Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.

On Jul, 12, 2026

42 people who take Lovenox and Optimark together, and have interactions are studied.

What are the common drug interactions of Lovenox and Optimark, by gender? *:

female:

Joint stiffness
Muscular weakness (muscle weakness)
Joint contracture (a permanent shortening of a muscle or joint)
Skin swelling
Gait disturbance
Skin hyperpigmentation (disorders affect the colour of your skin)
Arthralgia (joint pain)
Atrophy (wasting away of a part of the body)
Dry skin
Exfoliative rash (scaly red generalized skin rash)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Anxiety
Joint contracture (a permanent shortening of a muscle or joint)
Deformity (disfigurement)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Emotional distress
Skin fibrosis (fibrous tissue formation on skin)

What are the common drug interactions of Lovenox and Optimark, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Oedema peripheral (superficial swelling)
Pain in extremity
Skin hypertrophy (skin cells enlarges)
Skin tightness
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Myalgia (muscle pain)
Skin fibrosis (fibrous tissue formation on skin)
General physical health deterioration (weak health status)
Joint range of motion decreased (disease of joint movement)
Skin hypertrophy (skin cells enlarges)
Adverse event
Deformity (disfigurement)

50-59:

Rash papular (redness with papule)
Grip strength decreased
Joint swelling
Pruritus generalised (generalized itching)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Burning sensation
Fall
Hyperaesthesia

60+:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Hypoaesthesia (reduced sense of touch or sensation)
Muscle tightness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pruritus generalised (generalized itching)
Skin discolouration (change of skin colour)
Skin plaque (red, scaly patches to appear on the skin)
Anxiety
Injury

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 25 people, 59.52%
Pain: 8 people, 19.05%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 14.29%
Neuralgia (pain in one or more nerves): 4 people, 9.52%
High Blood Pressure: 4 people, 9.52%
Nuclear Magnetic Resonance Imaging Abdominal: 3 people, 7.14%
High Blood Cholesterol: 3 people, 7.14%
Anaemia (lack of blood): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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