Lovenox and Pegasys drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lovenox (enoxaparin sodium) and Pegasys (peginterferon alfa 2a). Common drug interactions include acute respiratory distress syndrome among females and acute generalised exanthematous pustulosis among males.
The phase IV clinical study analyzes what interactions people have when they take Lovenox and Pegasys. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.
What is Lovenox?
Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.
What is Pegasys?
Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.
47 people who take Lovenox and Pegasys together, and have interactions are studied.

What are the common drug interactions of Lovenox and Pegasys, by gender? *:
female:
- Acute respiratory distress syndrome
- Anaemia (lack of blood)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
- Neural tube defect (birth defects of the brain, spine, or spinal cord)
- Depression
- Face oedema (swelling of face)
- Foetal death (death of foetus)
- Hyperthermia (body temperature greatly above normal)
- Maternal exposure during pregnancy (use of substance during pregnancy)
male:
- Acute generalised exanthematous pustulosis (acute febrile drug eruption)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Toxic skin eruption (skin breakdown due to toxic substance)
- Death
- Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
- Swollen tongue (swelling of tongue)
- Congestive cardiomyopathy (weakening of heart muscle)
- Pulmonary alveolar haemorrhage (acute bleeding)
- Anxiety
- Blood cholesterol increased
What are the common drug interactions of Lovenox and Pegasys, by age (0-1 to 60+)? *:
0-1:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
2-9:
n/a
10-19:
n/a
20-29:
- Foetal death (death of foetus)
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Pulmonary alveolar haemorrhage (acute bleeding)
30-39:
- Acute respiratory distress syndrome
40-49:
- Acute respiratory distress syndrome
- Depression
- Face oedema (swelling of face)
- Hyperthermia (body temperature greatly above normal)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Neutropenia (an abnormally low number of neutrophils)
50-59:
- Acute generalised exanthematous pustulosis (acute febrile drug eruption)
- Anaemia (lack of blood)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Renal failure acute (rapid kidney dysfunction)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
- Swollen tongue (swelling of tongue)
- Blood cholesterol increased
- Chest pain
- Drug ineffective
60+:
- Rash
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Pneumonia
- Post thrombotic syndrome (long-term effects that can occur after venous thrombosis)
- Renal failure (kidney dysfunction)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Type 2 diabetes mellitus
- White blood cell count decreased
- Toxic skin eruption (skin breakdown due to toxic substance)
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 12.77%
- Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 10.64%
- Hypokalemia (low potassium): 4 people, 8.51%
- High Blood Pressure: 4 people, 8.51%
- Pain: 3 people, 6.38%
- Insomnia (sleeplessness): 3 people, 6.38%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.38%
- Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 6.38%
- Anaemia (lack of blood): 3 people, 6.38%
* Approximation only. Some reports may have incomplete information.
Do you take Lovenox and Pegasys?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lovenox and Pegasys:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lovenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pegasys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lovenox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pegasys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on enoxaparin sodium and peginterferon alfa 2a (the active ingredients of Lovenox and Pegasys, respectively), and Lovenox and Pegasys (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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