Lovenox and Pentasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lovenox (enoxaparin sodium) and Pentasa (mesalamine). Common drug interactions include areflexia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Lovenox and Pentasa. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

67 people who take Lovenox and Pentasa together, and have interactions are studied.

What are the common drug interactions of Lovenox and Pentasa, by gender? *:

female:

Areflexia (absence of a reflex)
Arthropathy
Ascites (accumulation of fluid in the abdominal cavity)
Ataxia (loss of full control of bodily movements)
Atrophy (wasting away of a part of the body)
Back pain
Balance disorder
Biliary cirrhosis (biliary cirrhosis occurs due to obstruction to the flow of bile through bile ducts either within the liver or outside the liver)
Blood corticotrophin decreased
Blood cortisol decreased

male:

Abdominal pain
Hospitalisation
Nephropathy (damage to or disease of a kidney)
Psoas abscess (collection of pus in the iliopsoas muscle compartment)
Rectal haemorrhage (bleeding from anus)
Renal atrophy (wasting of kidney)
Renal impairment (severely reduced kidney function)
Urinary tract infection
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Diarrhoea

What are the common drug interactions of Lovenox and Pentasa, by age (0-1 to 60+)? *:

0-1:

Bradycardia (abnormally slow heart action)
Dysmorphism (difference of body structure that is suggestive of a congenital disorder)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hypotonia neonatal (low muscle tone in neonatal)
Talipes

2-9:

n/a

10-19:

Anaemia (lack of blood)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Face oedema (swelling of face)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Myocarditis (inflammation of heart muscle myocardium)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombosis (formation of a blood clot inside a blood vessel)

20-29:

Abdominal pain
Hospitalisation
Inflammation
Migraine with aura (headache with vision weakness)
Depression
Rectal haemorrhage (bleeding from anus)
Drug resistance (reduction in effectiveness of a drug)
Anaemia (lack of blood)
Intestinal obstruction
Postoperative ileus

30-39:

Antepartum haemorrhage (bleeding from the vagina during pregnancy from the 24th week)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fall
Premature separation of placenta
Skeletal injury (bone and supporting muscle injury)
Upper respiratory tract infection
Viral infection
Drug exposure during pregnancy

40-49:

Hypoxia (low oxygen in tissues)
Lung disorder (lung disease)
Sputum purulent
Hepatocellular injury (liver injury)
Lung infection pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Death
Drug intolerance (drug sensitivity)
Infusion related reaction
Polyarthritis (arthritis which involves 5 or more joints simultaneously)

50-59:

Escherichia infection (bacterial infection by escherichia coli)
Hyperoxaluria (excessive urinary excretion of oxalate)
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Nephropathy (damage to or disease of a kidney)
Psoas abscess (collection of pus in the iliopsoas muscle compartment)
Renal atrophy (wasting of kidney)
Renal impairment (severely reduced kidney function)
Urinary tract infection
Vomiting

60+:

Thrombocytopenia (decrease of platelets in blood)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Vomiting
Hepatitis (inflammation of the liver)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Abdominal discomfort
Abdominal pain
Abdominal pain upper
Activities of daily living impaired
Acute myocardial infarction (acute heart attack)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 14.93%
Colitis (inflammation of colon): 9 people, 13.43%
Pain: 6 people, 8.96%
Asthma: 6 people, 8.96%
Immune System Disorder: 5 people, 7.46%
Depression: 4 people, 5.97%
Angioedema (rapid swelling of the dermis): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

Do you take Lovenox and Pentasa?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously