Lumigan and Rocephin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lumigan (bimatoprost) and Rocephin (ceftriaxone sodium). Common drug interactions include enterobacter test positive among females and syncope among males.
The phase IV clinical study analyzes what interactions people have when they take Lumigan and Rocephin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Lumigan?
Lumigan has active ingredients of bimatoprost. It is often used in glaucoma. eHealthMe is studying from 20,478 Lumigan users. Check the latest studies of Lumigan.
What is Rocephin?
Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
23 people who take Lumigan and Rocephin together, and have interactions are studied.

What are the common drug interactions of Lumigan and Rocephin, by gender? *:
female:
- Enterobacter test positive
- Fluid overload (too much fluid in the blood)
- Fracture
- Fungal infection
- Gastric disorder (disease of stomach)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- General physical health deterioration (weak health status)
- Haemoglobin decreased
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Histoplasmosis (infection caused by breathing in spores of a fungus)
male:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Pleural effusion (water on the lungs)
- Anaemia (lack of blood)
- Confusional state
- Dehydration (dryness resulting from the removal of water)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypoxia (low oxygen in tissues)
- Loss of consciousness
What are the common drug interactions of Lumigan and Rocephin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Injury
- International normalised ratio decreased
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Neck pain
- Prothrombin time shortened
- Pulmonary congestion (congestion in the lungs)
- Renal failure (kidney dysfunction)
- Sneezing
- Tremor (trembling or shaking movements in one or more parts of your body)
- Abdominal pain
60+:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Renal failure acute (rapid kidney dysfunction)
- Septic shock (shock due to blood infection)
- Diarrhoea
- General physical health deterioration (weak health status)
- Anaemia (lack of blood)
- Confusional state
- Dehydration (dryness resulting from the removal of water)
- Disease progression
- Drug hypersensitivity
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 39.13%
- Stress And Anxiety: 7 people, 30.43%
- Constipation: 7 people, 30.43%
- Pain: 7 people, 30.43%
- Diabetes: 6 people, 26.09%
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 21.74%
- Leukopenia (less number of white blood cells in blood): 5 people, 21.74%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
- Cardiac Failure Congestive: 4 people, 17.39%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 17.39%
* Approximation only. Some reports may have incomplete information.
Do you take Lumigan and Rocephin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lumigan and Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lumigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lumigan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocephin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bimatoprost and ceftriaxone sodium (the active ingredients of Lumigan and Rocephin, respectively), and Lumigan and Rocephin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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