Lupron depot and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lupron depot (leuprolide acetate) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lupron depot and Isosorbide dinitrate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lupron depot?

Lupron depot has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 27,037 Lupron depot users. Check the latest studies of Lupron depot.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

On Aug, 09, 2026

18 people who take Lupron depot and Isosorbide dinitrate together, and have interactions are studied.

Lupron depot and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Lupron Depot and Isosorbide Dinitrate, by gender? *:

female:

n/a

male:

Dyspnoea (difficult or laboured respiration)
Fall
Hypoxia (low oxygen in tissues)
Oedema lower limb (fluid collection in tissue of lower leg)
Upper respiratory tract infection
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hot flush (sudden feelings of heat)
Sluggishness (lacking alertness)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Haematuria present (presence of blood in urine due to trauma)

What are the common drug interactions of Lupron Depot and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dyspnoea (difficult or laboured respiration)
Fall
Hypoxia (low oxygen in tissues)
Oedema lower limb (fluid collection in tissue of lower leg)
Upper respiratory tract infection
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hot flush (sudden feelings of heat)
Sluggishness (lacking alertness)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Haematuria present (presence of blood in urine due to trauma)

What are the existing conditions these people have? *

Prostate Cancer: 9 people, 50.00%
Stress And Anxiety: 4 people, 22.22%
Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 4 people, 22.22%
Depression: 4 people, 22.22%
Urine Flow Decreased: 1 person, 5.56%
Stable Angina (a constant chest pain): 1 person, 5.56%
Prostate Cancer Stage Iv: 1 person, 5.56%
Oedema (fluid collection in tissue): 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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