Lynparza and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lynparza (olaparib) and Senna (senna). Common drug interactions include metastases to lung among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Lynparza and Senna. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Lynparza?

Lynparza has active ingredients of olaparib. eHealthMe is studying from 12,322 Lynparza users. Check the latest studies of Lynparza.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.



On Jul, 13, 2026

33 people who take Lynparza and Senna together, and have interactions are studied.

Lynparza and Senna drug interactions.

What are the common drug interactions of Lynparza and Senna, by gender? *:

female:

  1. Metastases to lung (cancer spreads to lung)
  2. Abdominal discomfort
  3. Anaemia (lack of blood)
  4. Bone pain
  5. Haemoglobin decreased
  6. Blood magnesium decreased
  7. Blood potassium decreased
  8. Breast cancer recurrent
  9. Cancer pain
  10. Cardiac infection (an infection of the heart)

male:

  1. Death
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Dysstasia (difficulty in standing)
  4. Platelet count decreased
  5. Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Lynparza and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Back pain
  2. Bone pain
  3. Dysgeusia (disorder of the sense of taste)

40-49:

  1. Death
  2. Arthralgia (joint pain)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Back pain
  5. Bone pain
  6. Breast cancer metastatic
  7. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  8. Diarrhoea
  9. Drug ineffective
  10. Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

  1. Anaemia (lack of blood)
  2. Blood magnesium decreased
  3. Blood potassium decreased
  4. Breast cancer recurrent
  5. Cancer pain
  6. Cardiac infection (an infection of the heart)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  9. Malignant neoplasm progression (cancer tumour came back)
  10. Metastases to abdominal cavity (cancer spreads to abdominal cavity)

60+:

  1. Anaemia macrocytic (a macrocytic class of anaemia)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Neuropathy peripheral (surface nerve damage)
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Weight decreased
  6. White blood cell count increased
  7. Death
  8. Fatigue (feeling of tiredness)
  9. Salivary hypersecretion (excess saliva secretion)
  10. Anxiety

What are the existing conditions these people have? *

  1. Ovarian Cancer (cancer of ovary): 20 people, 60.61%
  2. Insomnia (sleeplessness): 7 people, 21.21%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.18%
  4. High Blood Cholesterol: 6 people, 18.18%
  5. Stress And Anxiety: 3 people, 9.09%
  6. Blood Glucose Abnormal: 3 people, 9.09%
  7. Blood Pressure Abnormal: 3 people, 9.09%
  8. Bone Pain: 3 people, 9.09%
  9. Sleep Disorder: 3 people, 9.09%
  10. Indigestion: 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Lynparza and Senna?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lynparza and Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lynparza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lynparza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on olaparib and senna (the active ingredients of Lynparza and Senna, respectively), and Lynparza and Senna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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