Macrobid and Faslodex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) and Faslodex (fulvestrant). Common drug interactions include bone disorder among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Macrobid and Faslodex. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

What is Faslodex?

Faslodex has active ingredients of fulvestrant. It is often used in breast cancer metastatic. eHealthMe is studying from 19,255 Faslodex users. Check the latest studies of Faslodex.

On Aug, 06, 2026

43 people who take Macrobid and Faslodex together, and have interactions are studied.

Macrobid and Faslodex drug interactions.

What are the common drug interactions of Macrobid and Faslodex, by gender? *:

female:

Bone disorder
Constipation
Myalgia (muscle pain)
Stomatitis (inflammation of mucous membrane of mouth)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Cellulitis (infection under the skin)
Emotional distress
Facial pain
Gingival disorder (gum disease)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Gingival disorder (gum disease)
Heart rate irregular
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypertension (high blood pressure)
Injury
Neck pain
Oral candidiasis (fungal infection of mouth)
Osteolysis (dissolution of bone)

What are the common drug interactions of Macrobid and Faslodex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Scar
Acute sinusitis
Anaemia (lack of blood)
Angiopathy (generic term for a disease of the blood vessels)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthropathy
Back pain
Bone disorder

10-19:

n/a

20-29:

n/a

30-39:

Disease progression

40-49:

Abdominal pain
Arthralgia (joint pain)
Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Bone disorder
Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
Decreased interest
Defaecation urgency (a sudden compelling urge to defecate)
Depression
Dysfunctional uterine bleeding
Dyspnoea (difficult or laboured respiration)

50-59:

Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood cholesterol increased
Cardiac failure congestive
Cardiac murmur (an heart sound in valve abnormality)
Cardiomyopathy (weakening of the heart muscle)
Cluster headache (one-sided head pain with tearing)
Coma (state of unconsciousness lasting more than six hours)

60+:

Pain
Bone disorder
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cellulitis (infection under the skin)
Discomfort
Gingival bleeding (bleeding gums)
Gingival disorder (gum disease)
Heart rate irregular
Osteolysis (dissolution of bone)
Osteonecrosis of jaw (death of bone of jaw)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 19 people, 44.19%
Osteoporosis (bones weak and more likely to break): 17 people, 39.53%
Depression: 8 people, 18.60%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 18.60%
Pain: 4 people, 9.30%
Breast Cancer: 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

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