Macrobid and Lys drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) and Lys (lysine). Common drug interactions include alopecia among females.
The phase IV clinical study analyzes what interactions people have when they take Macrobid and Lys. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Macrobid?
Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.
What is Lys?
Lys has active ingredients of lysine. eHealthMe is studying from 16,532 Lys users. Check the latest studies of Lys.
31 people who take Macrobid and Lys together, and have interactions are studied.

What are the common drug interactions of Macrobid and Lys, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Depression
- Dermatitis diaper (diaper rash is a common form of inflamed skin)
- Dizziness
- Fatigue (feeling of tiredness)
- Feeding disorder (when children refuse to eat certain food groups)
- Feeling hot
- Gastrointestinal infection (infection of stomach and intestine)
- Hemiparesis (weakness on one side of the body)
- Hypersensitivity
male:
n/a
What are the common drug interactions of Macrobid and Lys, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Activities of daily living impaired
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Fear
- Injury
- Pain
- Painful respiration
- Pulmonary embolism (blockage of the main artery of the lung)
- Sleep disorder due to a general medical condition
30-39:
n/a
40-49:
- Allergy to animal
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Depression
- Diarrhoea
- Headache (pain in head)
- Infusion related reaction
- Injection site nerve damage
- Oral herpes (viral infection of mouth)
- Poor venous access
- Retching (strong involuntary effort to vomit)
- Stress
60+:
- Alopecia (absence of hair from areas of the body)
- Arthralgia (joint pain)
- Dizziness
- Fatigue (feeling of tiredness)
- Feeding disorder (when children refuse to eat certain food groups)
- Feeling hot
- Gastrointestinal infection (infection of stomach and intestine)
- Hemiparesis (weakness on one side of the body)
- Hypersensitivity
- Joint stiffness
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 22.58%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 19.35%
- High Blood Cholesterol: 5 people, 16.13%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.13%
- Gait Disturbance: 4 people, 12.90%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.90%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 12.90%
- Type 2 Diabetes: 3 people, 9.68%
- Diarrhea: 3 people, 9.68%
- High Blood Pressure: 3 people, 9.68%
* Approximation only. Some reports may have incomplete information.
Do you take Macrobid and Lys?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Macrobid and Lys:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Macrobid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Macrobid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline and lysine (the active ingredients of Macrobid and Lys, respectively), and Macrobid and Lys (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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