Macrobid and Rhinocort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) and Rhinocort (budesonide). Common drug interactions include back pain among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Macrobid and Rhinocort. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

What is Rhinocort?

Rhinocort has active ingredients of budesonide. It is often used in allergies. eHealthMe is studying from 7,139 Rhinocort users. Check the latest studies of Rhinocort.



On Jul, 30, 2026

71 people who take Macrobid and Rhinocort together, and have interactions are studied.

Macrobid and Rhinocort drug interactions.

What are the common drug interactions of Macrobid and Rhinocort, by gender? *:

female:

  1. Back pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Anxiety
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Bone disorder
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Aortic arteriosclerosis (hardening of the aortic arteries)
  9. Emotional distress
  10. Gait disturbance

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fall
  3. Aortic arteriosclerosis (hardening of the aortic arteries)
  4. Arthropathy
  5. Back pain
  6. Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  7. Bladder dysfunction
  8. Bone disorder
  9. Bone loss
  10. Candidiasis (candidiasis or thrush is a fungal infection)

What are the common drug interactions of Macrobid and Rhinocort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Scar
  2. Acute sinusitis
  3. Anaemia (lack of blood)
  4. Angiopathy (generic term for a disease of the blood vessels)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Aortic arteriosclerosis (hardening of the aortic arteries)
  8. Arthropathy
  9. Back pain
  10. Bone disorder

10-19:

  1. Abnormal weight gain
  2. Adverse reaction
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Cataract (clouding of the lens inside the eye)
  6. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Device expulsion
  10. Drug intolerance (drug sensitivity)

20-29:

n/a

30-39:

  1. Anxiety
  2. Borderline personality disorder
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Dizziness
  5. Headache (pain in head)
  6. Hot flush (sudden feelings of heat)
  7. Insomnia (sleeplessness)
  8. Irritability
  9. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  10. Social phobia (fear to go in social)

40-49:

  1. Back pain
  2. Gait disturbance
  3. Oedema peripheral (superficial swelling)
  4. Pain
  5. Asthma
  6. Pneumonia
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Anaemia (lack of blood)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

50-59:

  1. Asthenia (weakness)
  2. Bladder disorder
  3. Cardiovascular disorder (heart diseases)
  4. Cough
  5. Headache (pain in head)
  6. Insomnia (sleeplessness)
  7. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
  8. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  9. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  10. Tinnitus (a ringing in the ears)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pain
  3. Pain in jaw
  4. Spinal osteoarthritis (joint cartilage loss in spine)
  5. Bone disorder
  6. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  7. Gingival disorder (gum disease)
  8. Gingival oedema (swelling of gums)
  9. Gingivitis (inflammation of gums)
  10. Osteopenia (a condition where bone mineral density is lower than normal)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 29 people, 40.85%
  2. Depression: 21 people, 29.58%
  3. Pain: 20 people, 28.17%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 19 people, 26.76%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 19 people, 26.76%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 18.31%
  7. Allergic Rhinitis: 11 people, 15.49%
  8. Sinusitis (inflammation of sinus): 11 people, 15.49%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 15.49%
  10. Hypertriglyceridaemia (excess of triglycerides in the blood): 11 people, 15.49%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and Rhinocort?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Macrobid and Rhinocort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Macrobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rhinocort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Macrobid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rhinocort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline and budesonide (the active ingredients of Macrobid and Rhinocort, respectively), and Macrobid and Rhinocort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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