Macrobid and Ursodiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) and Ursodiol (ursodiol). Common drug interactions include impaired gastric emptying among females and blood urine present among males.

The phase IV clinical study analyzes what interactions people have when they take Macrobid and Ursodiol. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

On Jul, 26, 2026

26 people who take Macrobid and Ursodiol together, and have interactions are studied.

Macrobid and Ursodiol drug interactions.

What are the common drug interactions of Macrobid and Ursodiol, by gender? *:

female:

Impaired gastric emptying
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vocal cord disorder
Alopecia (absence of hair from areas of the body)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Pruritus (severe itching of the skin)
Acute hepatic failure
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Thrombocytopenia (decrease of platelets in blood)

male:

Blood urine present
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Neuropathy peripheral (surface nerve damage)
Pain
Cough
Death
Infection
Skin cancer

What are the common drug interactions of Macrobid and Ursodiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Acute hepatic failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug hypersensitivity
Fatigue (feeling of tiredness)
Hodgkin's disease (cancer originating from white blood cells)
Infection
Liver disorder (liver diseases)
Nausea (feeling of having an urge to vomit)
Oral surgery
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

Sleep Disorder: 5 people, 19.23%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 15.38%
Multiple Myeloma (cancer of the plasma cells): 4 people, 15.38%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 3 people, 11.54%
Anaemia (lack of blood): 3 people, 11.54%
Constipation: 3 people, 11.54%
Drowsiness: 3 people, 11.54%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 11.54%
Fluid Overload (too much fluid in the blood): 3 people, 11.54%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and Ursodiol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously