Magnesium hydroxide and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium hydroxide (magnesium) and Senna (senna). Common drug interactions include overdose among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium hydroxide and Senna. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium hydroxide?

Magnesium hydroxide has active ingredients of magnesium. eHealthMe is studying from 1,806 Magnesium hydroxide users. Check the latest studies of Magnesium hydroxide.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 20, 2026

76 people who take Magnesium hydroxide and Senna together, and have interactions are studied.

Magnesium hydroxide and Senna drug interactions.

What are the common drug interactions of Magnesium Hydroxide and Senna, by gender? *:

female:

Overdose
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Chest pain
Chronic kidney disease
Dysarthria (speech disorder)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Diarrhoea
Neutropenia (an abnormally low number of neutrophils)
Stomatitis (inflammation of mucous membrane of mouth)
Asthenia (weakness)
Blood lactic acid increased
Cardiac failure
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)

What are the common drug interactions of Magnesium Hydroxide and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Adenovirus infection
Anxiety
Nail picking
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

10-19:

n/a

20-29:

Anxiety
Dizziness
Dyspnoea (difficult or laboured respiration)
Injury
Malaise (a feeling of general discomfort or uneasiness)
Pain
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Adenoma benign (non-cancerous tumour -secreting)
Adnexa uteri cyst (ovarian cysts)
Allergic sinusitis

30-39:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pyrexia (fever)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)

40-49:

Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Ventricular fibrillation (abnormally irregular heart rhythm)
Chronic kidney disease
Death
Disease progression
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Crying
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Dehydration (dryness resulting from the removal of water)
Drug hypersensitivity
Eating disorder
Food craving
Genital abscess (build up of pus in genital)
Haematotoxicity (toxins that destroy red blood cells)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)

60+:

Fall
Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Neutropenia (an abnormally low number of neutrophils)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Blood pressure increased
Cardiac failure
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dysarthria (speech disorder)

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 27.63%
Pain: 20 people, 26.32%
Nausea (feeling of having an urge to vomit): 17 people, 22.37%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 15 people, 19.74%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 17.11%
Depression: 13 people, 17.11%
Insomnia (sleeplessness): 12 people, 15.79%
Oedema (fluid collection in tissue): 10 people, 13.16%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 10 people, 13.16%
Type 2 Diabetes: 9 people, 11.84%

* Approximation only. Some reports may have incomplete information.

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