Magnesium oxide and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium oxide (magnesium) and Botox (botulinum toxin type a). Common drug interactions include syncope among females and urinary retention among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium oxide and Botox. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium oxide?

Magnesium oxide has active ingredients of magnesium. It is often used in migraine. eHealthMe is studying from 19,022 Magnesium oxide users. Check the latest studies of Magnesium oxide.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.



On Jul, 30, 2026

71 people who take Magnesium oxide and Botox together, and have interactions are studied.

Magnesium oxide and Botox drug interactions.

What are the common drug interactions of Magnesium Oxide and Botox, by gender? *:

female:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Tonsillitis (inflammation of tonsil)
  3. Abdominal distension
  4. Allergy to arthropod sting
  5. Allergy to plants
  6. Ammonia increased
  7. Anxiety
  8. Appendicitis (inflammation of the appendix)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)

male:

  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Calculus bladder (bladder stone)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Fall
  5. Femur fracture
  6. Arrhythmia (irregular heartbeat)
  7. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  8. Dyspnoea (difficult or laboured respiration)
  9. Gastric disorder (disease of stomach)
  10. Head injury

What are the common drug interactions of Magnesium Oxide and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  3. Oxygen saturation decreased
  4. Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

n/a

20-29:

  1. Injection site pain
  2. Dizziness
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Migraine with aura (headache with vision weakness)
  6. Vomiting

30-39:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  3. Lip swelling
  4. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  5. Swelling face
  6. Swollen tongue (swelling of tongue)
  7. Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

  1. Pallor
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Appendicitis (inflammation of the appendix)
  5. Chest discomfort
  6. Depression
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastric disorder (disease of stomach)
  9. Herpes zoster
  10. Limb discomfort (discomfort in leg)

50-59:

  1. Abdominal pain
  2. Headache (pain in head)
  3. Impaired gastric emptying
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting
  6. Hypertension (high blood pressure)
  7. Abdominal distension
  8. Ammonia increased
  9. Arrhythmia (irregular heartbeat)
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Blood pressure increased
  3. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Urinary retention (the inability to completely or partially empty the bladder)
  6. Fall
  7. Influenza
  8. Infusion related reaction
  9. Pain
  10. Calculus bladder (bladder stone)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 23.94%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 19.72%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 16.90%
  4. Drowsiness: 7 people, 9.86%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.45%
  6. Constipation: 6 people, 8.45%
  7. Pain: 5 people, 7.04%
  8. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 7.04%
  9. High Blood Pressure: 5 people, 7.04%
  10. Nausea And Vomiting: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Magnesium oxide and Botox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Magnesium oxide and Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Magnesium oxide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium oxide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Botox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on magnesium and botulinum toxin type a (the active ingredients of Magnesium oxide and Botox, respectively), and Magnesium oxide and Botox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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