Malic acid and Aranesp drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Malic acid (alpha hydroxy acids) and Aranesp (darbepoetin alfa). Common drug interactions include bone disorder among females.
The phase IV clinical study analyzes what interactions people have when they take Malic acid and Aranesp. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Malic acid?
Malic acid has active ingredients of alpha hydroxy acids. It is often used in fibromyalgia. eHealthMe is studying from 246 Malic acid users. Check the latest studies of Malic acid.
What is Aranesp?
Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.
13 people who take Malic acid and Aranesp together, and have interactions are studied.

What are the common drug interactions of Malic Acid and Aranesp, by gender? *:
female:
- Bone disorder
- Cellulitis (infection under the skin)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gingival infection (gum infection)
- Gingival ulceration (ulcer on gums)
- Haemoglobin decreased
- Impaired healing
- Incisional drainage
- Mastication disorder (disease of chewing food)
- Neuropathy peripheral (surface nerve damage)
male:
n/a
What are the common drug interactions of Malic Acid and Aranesp, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Hyperkalaemia (damage to or disease of the kidney)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
50-59:
n/a
60+:
- Bone disorder
- Cellulitis (infection under the skin)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gingival infection (gum infection)
- Gingival ulceration (ulcer on gums)
- Haemoglobin decreased
- Impaired healing
- Incisional drainage
- Mastication disorder (disease of chewing food)
- Neuropathy peripheral (surface nerve damage)
What are the existing conditions these people have? *
- Stress And Anxiety: 12 people, 92.31%
- Pain: 12 people, 92.31%
- Metastases To Bone (cancer spreads to bone): 12 people, 92.31%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 12 people, 92.31%
- Gout (uric acid crystals building up in the body): 12 people, 92.31%
- Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 12 people, 92.31%
- Dizziness: 12 people, 92.31%
- Breast Cancer: 12 people, 92.31%
- Bone Pain: 12 people, 92.31%
- Bone Disorder: 12 people, 92.31%
* Approximation only. Some reports may have incomplete information.
Do you take Malic acid and Aranesp?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Malic acid (246 reports)
- Aranesp (54,331 reports)
Browse all drug interactions of Malic acid and Aranesp:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Malic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aranesp:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Malic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aranesp and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on alpha hydroxy acids and darbepoetin alfa (the active ingredients of Malic acid and Aranesp, respectively), and Malic acid and Aranesp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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