Malic acid and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Malic acid (alpha hydroxy acids) and Ibu (ibuprofen). Common drug interactions include injury among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Malic acid and Ibu. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Malic acid?

Malic acid has active ingredients of alpha hydroxy acids. It is often used in fibromyalgia. eHealthMe is studying from 246 Malic acid users. Check the latest studies of Malic acid.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Jul, 21, 2026

11 people who take Malic acid and Ibu together, and have interactions are studied.

What are the common drug interactions of Malic Acid and Ibu, by gender? *:

female:

Injury
Migraine (headache)
Abdominal distension
Activities of daily living impaired
Breast cancer
Chronic kidney disease
Diarrhoea
Drug dependence
Dysgeusia (disorder of the sense of taste)
Flatulence (flatus expelled through the anus)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)

What are the common drug interactions of Malic Acid and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug dependence
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

30-39:

n/a

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Impaired self-care
Incontinence (lack of moderation or self-control)
Injury
Migraine (headache)
Activities of daily living impaired

50-59:

Flatulence (flatus expelled through the anus)
Muscle spasms (muscle contraction)
Pruritus (severe itching of the skin)
Rash generalised (rash on most of body parts)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal distension
Breast cancer
Diarrhoea
Dysgeusia (disorder of the sense of taste)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Malaise (a feeling of general discomfort or uneasiness)
Nephrolithiasis (calculi in the kidneys)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 36.36%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 36.36%
Premenstrual Syndrome: 2 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
Thyroid Diseases: 1 person, 9.09%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Irritable Bowel Syndrome: 1 person, 9.09%
Indigestion: 1 person, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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