Marijuana and Aleve drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Marijuana (marijuana) and Aleve (naproxen sodium). Common drug interactions include fatigue among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Marijuana and Aleve. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Marijuana?

Marijuana has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 7,397 Marijuana users. Check the latest studies of Marijuana.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

On Jul, 18, 2026

45 people who take Marijuana and Aleve together, and have interactions are studied.

What are the common drug interactions of Marijuana and Aleve, by gender? *:

female:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Arrested labour
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Feeling hot
Insomnia (sleeplessness)
Leukocytosis (increased white blood cells)
Premature labour
Therapeutic response unexpected

male:

Fatigue (feeling of tiredness)
Road traffic accident
Insomnia (sleeplessness)
Lacrimation increased
Malaise (a feeling of general discomfort or uneasiness)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Pruritus (severe itching of the skin)
Rash
Rash papular (redness with papule)

What are the common drug interactions of Marijuana and Aleve, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cough
Faecaloma (hard mass of fecal matter)
Hot flush (sudden feelings of heat)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Vaginal haemorrhage (vaginal bleeding)

30-39:

Arrested labour
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Premature labour
Pruritus (severe itching of the skin)
Rash
Rash papular (redness with papule)
Skin exfoliation (removal of the oldest dead skin cells)
Alopecia (absence of hair from areas of the body)
Drug hypersensitivity
Fatigue (feeling of tiredness)

40-49:

Fatigue (feeling of tiredness)
Road traffic accident
Drug abuse
Impaired driving ability
Insomnia (sleeplessness)
Substance abuse
Balance disorder
Constipation
Decreased appetite
Diarrhoea

50-59:

Feeling hot
Therapeutic response unexpected
Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cholecystitis (infection of gallbladder)
Cough
Deafness
Deafness unilateral
Decreased appetite
Discomfort
Dizziness
Ear disorder
Eye movement disorder

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 26.67%
Insomnia (sleeplessness): 5 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.89%
Depression: 4 people, 8.89%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 8.89%
Swelling: 3 people, 6.67%
Nausea (feeling of having an urge to vomit): 3 people, 6.67%
Migraine (headache): 3 people, 6.67%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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