Marinol and Roxanol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Marinol (dronabinol) and Roxanol (morphine sulfate). Common drug interactions include bone pain among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Marinol and Roxanol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Marinol?

Marinol has active ingredients of dronabinol. It is often used in pain. eHealthMe is studying from 4,963 Marinol users. Check the latest studies of Marinol.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.



On Jul, 14, 2026

15 people who take Marinol and Roxanol together, and have interactions are studied.

Marinol and Roxanol drug interactions.

What are the common drug interactions of Marinol and Roxanol, by gender? *:

female:

  1. Bone pain
  2. Bone sarcoma (bone cancer)
  3. Brain neoplasm malignant (brain cancer tumour)
  4. Breast cancer metastatic
  5. Cardiac disorder
  6. Cardiac failure
  7. Catheter site infection (infection at the site of insertion)
  8. Chills (felling of cold)
  9. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  10. Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)

male:

  1. Infection
  2. Injury
  3. Anaemia (lack of blood)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Bone disorder
  7. Breast mass
  8. Calculus ureteric (stone in ureter)
  9. Cellulitis (infection under the skin)
  10. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the common drug interactions of Marinol and Roxanol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Infection
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Acne (skin problems that cause pimples)
  5. Alopecia (absence of hair from areas of the body)
  6. Anal fissure
  7. Anogenital warts
  8. Bacterial infection
  9. Bone erosion
  10. Bone sarcoma (bone cancer)

40-49:

  1. Abdominal pain upper
  2. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  3. Adrenal mass
  4. Agitation (state of anxiety or nervous excitement)
  5. Aortic valve incompetence
  6. Aphagia (inability or refusal to swallow)
  7. Arthralgia (joint pain)
  8. Asthenia (weakness)
  9. Atrophy (wasting away of a part of the body)
  10. Back pain

50-59:

  1. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  2. Confusional state
  3. Constipation
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Deformity (disfigurement)
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Diastolic dysfunction
  9. Disaccharide metabolism disorder (inherited metabolic disorder characterized by the deficiency or absence of the enzymes sucrase and isomaltase)
  10. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

  1. Asthenia (weakness)
  2. Pyrexia (fever)
  3. Cellulitis (infection under the skin)
  4. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  5. Costochondritis (chest wall pain)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Dental caries
  8. Disability
  9. Dyspepsia (indigestion)
  10. Epicondylitis (tennis elbow)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 7 people, 46.67%
  2. Breast Cancer Metastatic: 5 people, 33.33%
  3. Nausea (feeling of having an urge to vomit): 2 people, 13.33%
  4. Nausea And Vomiting: 1 person, 6.67%
  5. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 6.67%
  6. Lung Cancer Metastatic (lung cancer spreads to other parts): 1 person, 6.67%
  7. Itching: 1 person, 6.67%
  8. Diarrhea: 1 person, 6.67%
  9. Chronic Renal Failure (kidney failure): 1 person, 6.67%
  10. Cardiac Failure: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Marinol and Roxanol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Marinol and Roxanol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Marinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Roxanol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Marinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Roxanol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dronabinol and morphine sulfate (the active ingredients of Marinol and Roxanol, respectively), and Marinol and Roxanol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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