Mavik and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mavik (trandolapril) and Bextra (valdecoxib). Common drug interactions include back pain among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Mavik and Bextra. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Mavik?

Mavik has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 3,145 Mavik users. Check the latest studies of Mavik.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 12, 2026

32 people who take Mavik and Bextra together, and have interactions are studied.

What are the common drug interactions of Mavik and Bextra, by gender? *:

female:

Back pain
Bone swelling
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state
Emotional distress
Fall
Fibula fracture
Foot fracture

male:

Pain in extremity
Acute respiratory failure
Chills (felling of cold)
Depression
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)
Emotional distress

What are the common drug interactions of Mavik and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug toxicity
Lethargy (tiredness)
Multiple drug overdose accidental
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Blood creatine phosphokinase increased
Coma (state of unconsciousness lasting more than six hours)

60+:

Erythema (redness of the skin)
Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state
Emotional distress
Fall
Fibula fracture
Foot fracture
Hallucination (an experience involving the perception of something not present)
Infection

What are the existing conditions these people have? *

Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 10 people, 31.25%
Osteoporosis (bones weak and more likely to break): 10 people, 31.25%
Metastases To Bone (cancer spreads to bone): 10 people, 31.25%
Breast Cancer: 10 people, 31.25%
Spinal Osteoarthritis (joint cartilage loss in spine): 2 people, 6.25%
Pain In Extremity: 2 people, 6.25%
High Blood Cholesterol: 2 people, 6.25%
Diabetes: 2 people, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.25%
Breast Cancer Metastatic: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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