Mavik and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mavik (trandolapril) and Elavil (amitriptyline hydrochloride). Common drug interactions include leukocytosis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Mavik and Elavil. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Mavik?

Mavik has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 3,145 Mavik users. Check the latest studies of Mavik.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.



On Jul, 10, 2026

37 people who take Mavik and Elavil together, and have interactions are studied.

Mavik and Elavil drug interactions.

What are the common drug interactions of Mavik and Elavil, by gender? *:

female:

  1. Leukocytosis (increased white blood cells)
  2. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  3. Pancreatitis acute (sudden inflammation of pancreas)
  4. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  5. Parotid gland enlargement
  6. Pharyngolaryngeal pain
  7. Sinusitis (inflammation of sinus)
  8. Cough
  9. Increased upper airway secretion
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Asthenia (weakness)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Productive cough
  4. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
  5. Blood glucose increased
  6. Diarrhoea
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Dysuria (painful or difficult urination)
  9. Eye discharge
  10. Eye infection

What are the common drug interactions of Mavik and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

n/a

40-49:

  1. Influenza like illness
  2. Infusion related reaction
  3. Nephrolithiasis (calculi in the kidneys)
  4. Weight increased
  5. Abdominal distension
  6. Abdominal mass (localized enlargement or swelling in the human abdomen)
  7. Alanine aminotransferase increased
  8. Blood alkaline phosphatase nos increased

50-59:

  1. Eye infection
  2. Fatigue (feeling of tiredness)
  3. Infection
  4. Influenza
  5. Injection site haemorrhage (bleeding from injection site)
  6. Injection site pain
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Ocular hyperaemia (an abnormally large amount of blood in eye)
  10. Oropharyngeal pain

60+:

  1. Back pain
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Cough
  4. Drug dependence
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Hepatic steatosis (fatty liver disease)
  7. Leukocytosis (increased white blood cells)
  8. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  9. Pain
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Pain: 18 people, 48.65%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 15 people, 40.54%
  3. High Blood Cholesterol: 11 people, 29.73%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.11%
  5. Hepatitis C: 2 people, 5.41%
  6. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mavik and Elavil:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mavik:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mavik and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elavil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on trandolapril and amitriptyline hydrochloride (the active ingredients of Mavik and Elavil, respectively), and Mavik and Elavil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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