Mavik and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mavik (trandolapril) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include focal segmental glomerulosclerosis among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Mavik and Percocet. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Mavik?

Mavik has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 3,145 Mavik users. Check the latest studies of Mavik.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

45 people who take Mavik and Percocet together, and have interactions are studied.

What are the common drug interactions of Mavik and Percocet, by gender? *:

female:

Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Tenderness (pain or discomfort when an affected area is touched)
Anxiety
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Injury
Vertigo
Abdominal pain
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)

male:

Drug dependence
Headache (pain in head)
Chest pain
Confusional state
Dizziness
Postoperative infection
Disturbance in attention
Dyspnoea exertional (breathlessness or shortness of breath)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity

What are the common drug interactions of Mavik and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Fear of pregnancy
General physical health deterioration (weak health status)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

40-49:

Suicidal ideation
Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperaesthesia
Night sweats (sweating in night)
Tenderness (pain or discomfort when an affected area is touched)
Nausea (feeling of having an urge to vomit)

50-59:

Limb injury
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
Blood creatine phosphokinase increased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

60+:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Adrenal mass
Bone swelling
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Confusional state
Dizziness
Erythema (redness of the skin)
Fall

What are the existing conditions these people have? *

Depression: 12 people, 26.67%
Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 10 people, 22.22%
Osteoporosis (bones weak and more likely to break): 10 people, 22.22%
Metastases To Bone (cancer spreads to bone): 10 people, 22.22%
Breast Cancer: 10 people, 22.22%
High Blood Cholesterol: 6 people, 13.33%
Chest Pain: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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