Maxair and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxair (pirbuterol acetate) and Astelin (azelastine hydrochloride). Common drug interactions include dysuria among females and influenza like illness among males.

The phase IV clinical study analyzes what interactions people have when they take Maxair and Astelin. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Maxair?

Maxair has active ingredients of pirbuterol acetate. It is often used in asthma. eHealthMe is studying from 2,903 Maxair users. Check the latest studies of Maxair.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

64 people who take Maxair and Astelin together, and have interactions are studied.

What are the common drug interactions of Maxair and Astelin, by gender? *:

female:

Dysuria (painful or difficult urination)
Endometrial disorder
Fasciitis (infection of muscle surrounding tissue)
Gastric bypass
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Head injury
Hydronephrosis (water inside the kidney)
Injection site erythema (redness at injection site)
Injection site infection

male:

Influenza like illness
Nausea (feeling of having an urge to vomit)
Foot fracture
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematochezia (passage of stools containing blood)
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Anger
Anxiety
Arthropathy

What are the common drug interactions of Maxair and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hallucination (an experience involving the perception of something not present)

10-19:

Anger
Drug effect decreased
Dry mouth
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)
Infection
Insomnia (sleeplessness)
Mood swings (an extreme or rapid change in mood)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stomach discomfort (pain in abdomen)

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Concussion (short loss of normal brain function in response to a head injury)
Fasciitis (infection of muscle surrounding tissue)
Head injury
Injection site erythema (redness at injection site)
Injection site infection
Injection site pain
Migraine (headache)
Myositis (inflammation of the muscles)
Oedema peripheral (superficial swelling)

40-49:

Stent placement
Thyroid cancer
Anaemia (lack of blood)
Bedridden
Blood iron decreased
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Chest discomfort
Death
Dizziness

50-59:

Tremor (trembling or shaking movements in one or more parts of your body)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Biliary dilatation
Blood bicarbonate decreased
Blood glucose increased
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)

60+:

Nausea (feeling of having an urge to vomit)
Anxiety
Oral pain
Respiratory distress (difficulty in breathing)
Suicidal ideation
Vascular injury
Weight decreased
Cataract (clouding of the lens inside the eye)
Corneal abrasion (loss of the surface of cornea)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 20.31%
Pain: 9 people, 14.06%
Muscle Spasms (muscle contraction): 9 people, 14.06%
Hypersensitivity: 8 people, 12.50%
High Blood Pressure: 8 people, 12.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 12.50%
High Blood Cholesterol: 7 people, 10.94%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 6 people, 9.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 7.81%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 7.81%

* Approximation only. Some reports may have incomplete information.

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