Maxalt-mlt and Tecfidera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt-mlt (rizatriptan benzoate) and Tecfidera (dimethyl fumarate). Common drug interactions include white blood cell count decreased among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt-mlt and Tecfidera. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt-mlt?

Maxalt-mlt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,534 Maxalt-mlt users. Check the latest studies of Maxalt-mlt.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

18 people who take Maxalt-mlt and Tecfidera together, and have interactions are studied.

Maxalt-mlt and Tecfidera drug interactions.

What are the common drug interactions of Maxalt-Mlt and Tecfidera, by gender? *:

female:

White blood cell count decreased
Joint injury
Post-traumatic pain
Lymphocyte count decreased
Anxiety
Drug ineffective
Pain
Abdominal discomfort
Fall
Affective disorder (mental disorder)

male:

Abdominal discomfort
Abdominal pain upper
Colitis ulcerative (inflammation of colon with ulcer)
Decreased appetite
Gait disturbance
Malaise (a feeling of general discomfort or uneasiness)
Upper respiratory tract infection

What are the common drug interactions of Maxalt-Mlt and Tecfidera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Muscular weakness (muscle weakness)

50-59:

Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Affective disorder (mental disorder)
Back pain
Blood glucose increased
Blood urea increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Delirium (wild excitement)
Depression
Failure to thrive (inadequate weight gain and physical growth in children)

60+:

n/a

What are the existing conditions these people have? *

Gait Disturbance: 7 people, 38.89%
Pain: 1 person, 5.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.56%
Muscle Spasms (muscle contraction): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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