Maxalt and Alendronate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Alendronate sodium (alendronate sodium). Common drug interactions include rib fracture among females and chronic obstructive pulmonary disease among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Alendronate sodium. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.



On Jul, 06, 2026

82 people who take Maxalt and Alendronate sodium together, and have interactions are studied.

Maxalt and Alendronate sodium drug interactions.

What are the common drug interactions of Maxalt and Alendronate Sodium, by gender? *:

female:

  1. Rib fracture
  2. Urinary tract infection
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Hypertension (high blood pressure)
  9. Influenza
  10. Heart rate increased

male:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Oedema peripheral (superficial swelling)
  3. Bone disorder
  4. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  7. Cellulitis (infection under the skin)
  8. Compression fracture (fracture due to pressure caused by injury)
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Craniocerebral injury (injury to cranium and brain)

What are the common drug interactions of Maxalt and Alendronate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Constipation
  2. Nasopharyngitis (inflammation of the nasopharynx)
  3. Upper-airway cough syndrome

30-39:

  1. Loss of consciousness
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Juvenile myoclonic epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years)
  4. Heart rate increased
  5. Hospitalisation
  6. Cardiac arrest
  7. Depression
  8. Emotional distress
  9. Fall
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus)

40-49:

  1. Fatigue (feeling of tiredness)
  2. Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
  3. Alanine aminotransferase increased
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Aspartate aminotransferase increased
  7. Back pain
  8. Blood sodium decreased
  9. Blood uric acid decreased
  10. Chest pain

50-59:

  1. Back pain
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  6. Decreased appetite
  7. Drug ineffective
  8. Femur fracture
  9. Hand fracture
  10. Headache (pain in head)

60+:

  1. Urinary tract infection
  2. Headache (pain in head)
  3. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  4. Anaemia (lack of blood)
  5. Back injury
  6. Blepharitis (chronic inflammation of the eyelid)
  7. Blood disorder
  8. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  9. Bone pain
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 38 people, 46.34%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 32 people, 39.02%
  3. Pain: 8 people, 9.76%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 8.54%
  5. Depression: 7 people, 8.54%
  6. Cystitis Interstitial (unknown cause characterized by bladder pain): 6 people, 7.32%
  7. Muscle Spasms (muscle contraction): 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Maxalt and Alendronate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alendronate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alendronate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on rizatriptan benzoate and alendronate sodium (the active ingredients of Maxalt and Alendronate sodium, respectively), and Maxalt and Alendronate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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