Maxalt and Geodon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Geodon (ziprasidone hydrochloride). Common drug interactions include bladder pain among females and serotonin syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Geodon. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,505 Geodon users. Check the latest studies of Geodon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

69 people who take Maxalt and Geodon together, and have interactions are studied.

What are the common drug interactions of Maxalt and Geodon, by gender? *:

female:

Bladder pain
Blood potassium decreased
Blood pressure increased
Bone pain
Borderline personality disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac flutter (abnormal heart rhythm)
Chest pain
Chronic kidney disease

male:

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Urinary tract infection
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Chills (felling of cold)
Hyperhidrosis (abnormally increased sweating)
Hyperreflexia (overactive or over responsive reflexes)

What are the common drug interactions of Maxalt and Geodon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cholecystitis (infection of gallbladder)
Borderline personality disorder
Pain

20-29:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pain
Confusional state
Headache (pain in head)
Metrorrhagia (uterine bleeding at irregular intervals)
Urinary tract infection
Cholecystitis chronic (long lasting infection of gallbladder)
Abnormal behaviour
Aggression
Aphasia (damage to the parts of the brain that control language)

30-39:

Myositis (inflammation of the muscles)
Obsessive rumination (thinking and worry or rumination is an inability to gain control over recurrent, distressing thoughts, images)
Panic attack
Panic disorder
Papilloma viral infection
Psychotic disorder
Salivary hypersecretion (excess saliva secretion)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Sinusitis (inflammation of sinus)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Abdominal discomfort
Accident
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Arrhythmia (irregular heartbeat)
Back pain
Bladder pain
Blood cholesterol increased
Blood pressure increased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac flutter (abnormal heart rhythm)

50-59:

Fall
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Urinary tract infection
Bladder dysfunction
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory failure (inadequate gas exchange by the respiratory system)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Bladder disorder

60+:

Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Bladder dysfunction
Fall
Hyperbilirubinaemia (excess of bilirubin in the blood)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 22 people, 31.88%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 19 people, 27.54%
Pain: 18 people, 26.09%
Depression: 16 people, 23.19%
Fibromyalgia (a long-term condition which causes pain all over the body): 16 people, 23.19%
Stress And Anxiety: 15 people, 21.74%
Sleep Disorder: 12 people, 17.39%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.04%
Hypersensitivity: 9 people, 13.04%
Cystitis Interstitial (unknown cause characterized by bladder pain): 9 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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