Maxalt and Mysoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Mysoline (primidone). Common drug interactions include arthropathy among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Mysoline. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

On Jul, 07, 2026

16 people who take Maxalt and Mysoline together, and have interactions are studied.

What are the common drug interactions of Maxalt and Mysoline, by gender? *:

female:

Arthropathy
Chest pain
Chest pressure sensation (feeling of pressure on chest)
Dental caries
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sweating increased (excess sweating)

male:

Drug ineffective
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Malaise (a feeling of general discomfort or uneasiness)
Renal disorder (kidney disease)
Blood pressure increased
Blood sodium decreased
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Ankylosing spondylitis (type of arthritis affecting the spine)
Arthralgia (joint pain)
Cardiac arrest

What are the common drug interactions of Maxalt and Mysoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood pressure increased
Blood sodium decreased
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Ankylosing spondylitis (type of arthritis affecting the spine)
Arthralgia (joint pain)
Drug ineffective
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

50-59:

Chest pain
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
Chest pressure sensation (feeling of pressure on chest)
Dental caries
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sweating increased (excess sweating)

60+:

Arthropathy

What are the existing conditions these people have? *

Thyroid Diseases: 6 people, 37.50%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 31.25%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 31.25%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 12.50%
Depression: 2 people, 12.50%
Pain: 2 people, 12.50%
Vitamin B12 Deficiency: 1 person, 6.25%
Hypotension (abnormally low blood pressure): 1 person, 6.25%
Back Pain: 1 person, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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