Maxalt and Vitamin b2 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Vitamin b2 (riboflavin). Common drug interactions include fatigue among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Vitamin b2. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Vitamin b2?

Vitamin b2 has active ingredients of riboflavin. It is often used in migraine. eHealthMe is studying from 1,740 Vitamin b2 users. Check the latest studies of Vitamin b2.



On Jul, 13, 2026

50 people who take Maxalt and Vitamin b2 together, and have interactions are studied.

Maxalt and Vitamin b2 drug interactions.

What are the common drug interactions of Maxalt and Vitamin B2, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Visual impairment
  3. White blood cell count decreased
  4. Drug ineffective
  5. Infusion related reaction
  6. Joint injury
  7. Memory impairment
  8. Pain
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Weight decreased

male:

  1. Death
  2. Hypersensitivity
  3. Insomnia (sleeplessness)

What are the common drug interactions of Maxalt and Vitamin B2, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
  2. Adrenal mass
  3. Adverse drug reaction
  4. Anxiety
  5. Blood testosterone free increased
  6. Decreased appetite
  7. Derealisation
  8. Diarrhoea
  9. Fatigue (feeling of tiredness)
  10. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

30-39:

  1. Abasia (inability to walk)
  2. Application site erythema (redness of the skin at application site)
  3. Application site inflammation
  4. Application site pain
  5. Application site reaction
  6. Application site vesicles (small bubble within a cell at application site)
  7. Application site warmth
  8. Burns second degree
  9. Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)

40-49:

  1. Headache (pain in head)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Anger
  4. Antinuclear antibody positive
  5. Asthenia (weakness)
  6. Blood pressure increased
  7. Death
  8. Depression
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

50-59:

  1. Cellulitis (infection under the skin)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Road traffic accident
  4. Joint injury
  5. Drug ineffective
  6. Post-traumatic pain
  7. White blood cell count decreased
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Anxiety
  10. Back pain

60+:

  1. Dizziness
  2. Dyspnoea (difficult or laboured respiration)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  5. Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Fall
  8. Infection
  9. Infusion related reaction
  10. Lymphadenopathy (disease or enlargement of lymph nodes)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 22.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 20.00%
  3. Gait Disturbance: 10 people, 20.00%
  4. Headache (pain in head): 7 people, 14.00%
  5. Pain: 6 people, 12.00%
  6. Immunodeficiency Common Variable: 4 people, 8.00%
  7. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 3 people, 6.00%
  8. High Blood Pressure: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Maxalt and Vitamin b2?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Maxalt and Vitamin b2:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin b2:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b2 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rizatriptan benzoate and riboflavin (the active ingredients of Maxalt and Vitamin b2, respectively), and Maxalt and Vitamin b2 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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