Maxide and Niaspan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxide (hydrochlorothiazide; triamterene) and Niaspan (niacin). Common drug interactions include flushing among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Maxide and Niaspan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Maxide?

Maxide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 304 Maxide users. Check the latest studies of Maxide.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

On Jul, 08, 2026

13 people who take Maxide and Niaspan together, and have interactions are studied.

What are the common drug interactions of Maxide and Niaspan, by gender? *:

female:

Flushing (the warm, red condition of human skin)
Blood glucose increased
Asthenia (weakness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Heart rate increased
Myalgia (muscle pain)
Constipation
Fatigue (feeling of tiredness)
Muscle cramps (painful sensations caused by muscle contraction)
Night sweats (sweating in night)

male:

Flushing (the warm, red condition of human skin)
Burning sensation
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dry mouth
Hot flush (sudden feelings of heat)
Incision site pain
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Tongue discolouration (colour change of tongue)

What are the common drug interactions of Maxide and Niaspan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Muscle cramps (painful sensations caused by muscle contraction)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

60+:

Flushing (the warm, red condition of human skin)
Asthenia (weakness)
Blood glucose increased
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the existing conditions these people have? *

Low Density Lipoprotein: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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