Maxipime and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxipime (cefepime hydrochloride) and Soliris (eculizumab). Common drug interactions include renal impairment among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Maxipime and Soliris. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Maxipime?

Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 20, 2026

11 people who take Maxipime and Soliris together, and have interactions are studied.

What are the common drug interactions of Maxipime and Soliris, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Oedema (fluid collection in tissue)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Serum ferritin increased
Pericardial effusion (fluid around the heart)
Altered state of consciousness (altered state of mind)
Nephrogenic anaemia (anaemia due to kidney disease)
Drug ineffective

male:

Cardiac arrest
Cerebral venous thrombosis (clot in brains venous blood system)
Aortic thrombosis (formation of a blood clot inside aorta)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Fungal peritonitis (fungal infection silk like membrane lines inner abdominal wall)
Intra-abdominal haemorrhage (intra-abdominal bleeding)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Peritoneal candidiasis (fungal infection in peritoneal)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)

What are the common drug interactions of Maxipime and Soliris, by age (0-1 to 60+)? *:

0-1:

Cardiac arrest
Cerebral venous thrombosis (clot in brains venous blood system)
Haemorrhagic diathesis (bleeding tendency)
Hypertension (high blood pressure)
Platelet count decreased
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Aortic thrombosis (formation of a blood clot inside aorta)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)

2-9:

Drug ineffective
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
Septic shock (shock due to blood infection)

10-19:

Pericardial effusion (fluid around the heart)
Renal impairment (severely reduced kidney function)
Acne (skin problems that cause pimples)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Blood product transfusion dependent
Bone marrow failure
Contusion (a type of hematoma of tissue in which capillaries)
Fatigue (feeling of tiredness)
Gingival bleeding (bleeding gums)
Irritable bowel syndrome

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Altered state of consciousness (altered state of mind)
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Oedema (fluid collection in tissue)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Renal impairment (severely reduced kidney function)
Serum ferritin increased
Nasopharyngitis (inflammation of the nasopharynx)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Pericardial effusion (fluid around the heart)

What are the existing conditions these people have? *

Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 8 people, 72.73%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 5 people, 45.45%
High Blood Pressure: 4 people, 36.36%
Infection: 3 people, 27.27%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 2 people, 18.18%
Fever: 2 people, 18.18%
Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 2 people, 18.18%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 18.18%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 18.18%
Rashes (redness): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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