Maxitrol and Cosopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxitrol (dexamethasone; neomycin sulfate; polymyxin b sulfate) and Cosopt (dorzolamide hydrochloride; timolol maleate). Common drug interactions include suture related complication among females and intraocular pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Maxitrol and Cosopt. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Maxitrol?

Maxitrol has active ingredients of dexamethasone; neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 986 Maxitrol users. Check the latest studies of Maxitrol.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.



On Aug, 05, 2026

11 people who take Maxitrol and Cosopt together, and have interactions are studied.

Maxitrol and Cosopt drug interactions.

What are the common drug interactions of Maxitrol and Cosopt, by gender? *:

female:

  1. Suture related complication
  2. Eye irritation
  3. Intraocular pressure increased
  4. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  5. Vitritis (inflammation of the vitreous humour of the eye)

male:

  1. Intraocular pressure increased
  2. Corneal deposits
  3. Death
  4. Drug ineffective
  5. Eczema eyelids (patches of skin become rough and inflamed, with itching and bleeding blisters on eyelid)
  6. Eye discharge
  7. Eyelid infection
  8. Eyelid ptosis (falling of the upper or lower eyelid)
  9. Lung adenocarcinoma (a form of non-small cell lung cancer)
  10. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)

What are the common drug interactions of Maxitrol and Cosopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Intraocular pressure increased
  2. Ocular hypertension (intraocular pressure higher than normal)

10-19:

  1. Intraocular pressure increased

20-29:

  1. Suture related complication
  2. Eye irritation
  3. Intraocular pressure increased
  4. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  5. Vitritis (inflammation of the vitreous humour of the eye)

30-39:

n/a

40-49:

n/a

50-59:

  1. Corneal deposits
  2. Corneal erosion (failure of the cornea's outermost layer of epithelial cells to attach to the underlying)
  3. Intraocular pressure increased

60+:

  1. Cataract (clouding of the lens inside the eye)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Eyelid infection
  4. Eyelid ptosis (falling of the upper or lower eyelid)
  5. Lung adenocarcinoma (a form of non-small cell lung cancer)
  6. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  7. Retinal haemorrhage (bleeding from retina)
  8. Retinopathy proliferative (a condition in which very small blood vessels grow from the surface of the retina and damages retina)
  9. Skin discolouration (change of skin colour)
  10. Vision blurred

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 4 people, 36.36%
  2. High Blood Pressure: 4 people, 36.36%
  3. Pain In Extremity: 2 people, 18.18%
  4. High Blood Cholesterol: 2 people, 18.18%
  5. Gout (uric acid crystals building up in the body): 2 people, 18.18%
  6. Eye Injury: 2 people, 18.18%
  7. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 18.18%
  8. Cardiac Failure Congestive: 2 people, 18.18%
  9. Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 18.18%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Maxitrol and Cosopt?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Maxitrol and Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosopt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone; neomycin sulfate; polymyxin b sulfate and dorzolamide hydrochloride; timolol maleate (the active ingredients of Maxitrol and Cosopt, respectively), and Maxitrol and Cosopt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: