Maxolon and Aldactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxolon (metoclopramide hydrochloride) and Aldactone (spironolactone). Common drug interactions include pneumonia among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Maxolon and Aldactone. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Maxolon?

Maxolon has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,977 Maxolon users. Check the latest studies of Maxolon.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

On Jul, 17, 2026

25 people who take Maxolon and Aldactone together, and have interactions are studied.

Maxolon and Aldactone drug interactions.

What are the common drug interactions of Maxolon and Aldactone, by gender? *:

female:

Pneumonia
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Gamma-glutamyltransferase increased
Blood urea nitrogen/creatinine ratio increased
Cellulitis (infection under the skin)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Gastroenteritis (inflammation of stomach and intestine)
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Lymphocyte count decreased
Neutropenia (an abnormally low number of neutrophils)

male:

Ascites (accumulation of fluid in the abdominal cavity)
Dyspnoea (difficult or laboured respiration)
Cardiac failure
Metastases to bone (cancer spreads to bone)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Lethargy (tiredness)
Renal failure acute (rapid kidney dysfunction)
Blood creatinine increased
Hyperkalaemia (damage to or disease of the kidney)

What are the common drug interactions of Maxolon and Aldactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Epistaxis (bleed from the nose)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Inflammation
Irritable bowel syndrome
Menstrual disorder (disease of menstrual cycle)
Overweight
Pain
Rash

30-39:

n/a

40-49:

n/a

50-59:

Cellulitis (infection under the skin)
Rectal abscess (pus in rectum)
Diarrhoea
Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)

60+:

Ascites (accumulation of fluid in the abdominal cavity)
Dyspnoea (difficult or laboured respiration)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Gastroenteritis (inflammation of stomach and intestine)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Lymphocyte count decreased
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 32.00%
Constipation: 7 people, 28.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 24.00%
Depression: 6 people, 24.00%
Diarrhea: 5 people, 20.00%
Pain: 5 people, 20.00%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 16.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 16.00%
Ascites (accumulation of fluid in the abdominal cavity): 4 people, 16.00%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 16.00%

* Approximation only. Some reports may have incomplete information.

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