Maxolon and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxolon (metoclopramide hydrochloride) and Phenergan (promethazine hydrochloride). Common drug interactions include pyrexia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Maxolon and Phenergan. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Maxolon?

Maxolon has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,977 Maxolon users. Check the latest studies of Maxolon.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

On Jul, 20, 2026

51 people who take Maxolon and Phenergan together, and have interactions are studied.

Maxolon and Phenergan drug interactions.

What are the common drug interactions of Maxolon and Phenergan, by gender? *:

female:

Pyrexia (fever)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Neutropenia (an abnormally low number of neutrophils)
Pain
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaemia (lack of blood)
Cough
Dyspnoea (difficult or laboured respiration)
Gastrointestinal obstruction
Intestinal obstruction

male:

Pyrexia (fever)
Aggression
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Neutropenia (an abnormally low number of neutrophils)
Oral candidiasis (fungal infection of mouth)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Suicidal ideation
Suicide attempt
Renal impairment (severely reduced kidney function)

What are the common drug interactions of Maxolon and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Multi-organ failure (multisystem organ failure)

10-19:

n/a

20-29:

Suicide attempt
Blood alkaline phosphatase decreased
Parathyroid tumour benign (parathyroid tumour non-cancerous)
Proteus infection (proteus can cause urinary tract infections)
Aggression
Agitation (state of anxiety or nervous excitement)
Delusion (a false belief or opinion)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hallucination, visual (seeing things that aren't there)
Homicidal ideation (thoughts about human killing another human)

30-39:

Pain
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaemia (lack of blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Cardiac arrest
Colitis (inflammation of colon)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Hypotension (abnormally low blood pressure)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)

40-49:

Pyrexia (fever)
Abdominal pain
Arthralgia (joint pain)
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fatigue (feeling of tiredness)
Gastritis (inflammation of stomach)
Haematochezia (passage of stools containing blood)
Headache (pain in head)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal obstruction
Intestinal obstruction
Intestinal perforation (complete penetration of the wall of the intestine)
Adverse drug reaction
Anaemia (lack of blood)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pain
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

60+:

Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Blood potassium decreased
Haematocrit decreased
Weight decreased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Death
Digoxin toxicity

What are the existing conditions these people have? *

Pain: 13 people, 25.49%
Constipation: 12 people, 23.53%
Nausea And Vomiting: 6 people, 11.76%
Asthma: 6 people, 11.76%
Fever: 6 people, 11.76%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 11.76%
Ovarian Cancer (cancer of ovary): 5 people, 9.80%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 9.80%
Ill-Defined Disorder: 5 people, 9.80%
Stress And Anxiety: 5 people, 9.80%

* Approximation only. Some reports may have incomplete information.

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