Maxzide and Adipex-p drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Adipex-p (phentermine hydrochloride). Common drug interactions include chest pain among females.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Adipex-p. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Adipex-p?

Adipex-p has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 2,718 Adipex-p users. Check the latest studies of Adipex-p.

On Jul, 06, 2026

25 people who take Maxzide and Adipex-p together, and have interactions are studied.

What are the common drug interactions of Maxzide and Adipex-P, by gender? *:

female:

Chest pain
Cardiovascular disorder (heart diseases)
Headache (pain in head)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Malaise (a feeling of general discomfort or uneasiness)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Splenomegaly (enlargement of spleen)
Blood bilirubin increased
Depression

male:

n/a

What are the common drug interactions of Maxzide and Adipex-P, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Drug ineffective
Pain
Abortion (termination of pregnancy)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthma
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Chest tightness

40-49:

Proteinuria present
Prothrombin level increased
Secondary polycythaemia (natural or artificial increases in the production of erythropoietin)
Sore throat (pain or irritation of the throat)
Sweating increased (excess sweating)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Valvular heart disease (diseases of the heart valves)
Viral infection
White blood cell count decreased
Fatigue (feeling of tiredness)

50-59:

Chest pain
Dry mouth
Keratoconjunctivitis (inflammation of the cornea and conjunctiva)
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Valvular heart disease (diseases of the heart valves)
Anxiety
Headache (pain in head)
Injury
Oedema peripheral (superficial swelling)
Pain

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arrhythmia (irregular heartbeat)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 8.00%
Pain: 2 people, 8.00%
Oedema (fluid collection in tissue): 2 people, 8.00%
Nausea And Vomiting: 2 people, 8.00%
Nausea (feeling of having an urge to vomit): 2 people, 8.00%
Multiple Allergies (allergy to multiple agents): 2 people, 8.00%
Inflammation: 2 people, 8.00%
Infection: 2 people, 8.00%
High Blood Cholesterol: 2 people, 8.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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