Maxzide and Augmentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include bacteraemia among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Augmentin. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

On Jul, 21, 2026

56 people who take Maxzide and Augmentin together, and have interactions are studied.

Maxzide and Augmentin drug interactions.

What are the common drug interactions of Maxzide and Augmentin, by gender? *:

female:

Bacteraemia (presence of bacteria in the blood)
Blood cholesterol increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Emotional distress
Febrile neutropenia (fever with reduced white blood cells)
Fungaemia (fungi circulate in the blood)

male:

Cough
Pyrexia (fever)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Skin reaction
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abscess limb (limb infection)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arthralgia (joint pain)
Back pain

What are the common drug interactions of Maxzide and Augmentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Thrombosis (formation of a blood clot inside a blood vessel)
Wegener's granulomatosis (inflammation of the blood vessels lungs sinuses)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abscess limb (limb infection)
Balanoposthitis (inflammation of the glands penis and the foreskin)

50-59:

Emotional distress
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemophilus infection (bacterial infection by haemophilus influenzae)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pain
Polytraumatism (multiple trauma)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Chronic kidney disease
Cough
Skin reaction
Bacteraemia (presence of bacteria in the blood)
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Death
Febrile neutropenia (fever with reduced white blood cells)
Fungaemia (fungi circulate in the blood)

What are the existing conditions these people have? *

Pain: 11 people, 19.64%
High Blood Cholesterol: 8 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 14.29%
Diabetes: 8 people, 14.29%
Multiple Allergies (allergy to multiple agents): 5 people, 8.93%
Type 2 Diabetes: 4 people, 7.14%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 7.14%
Neuralgia (pain in one or more nerves): 4 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 7.14%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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