Maxzide and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Cyclophosphamide (cyclophosphamide). Common drug interactions include hypokalaemia among females and bone disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Cyclophosphamide. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.



On Jul, 11, 2026

18 people who take Maxzide and Cyclophosphamide together, and have interactions are studied.

Maxzide and Cyclophosphamide drug interactions.

What are the common drug interactions of Maxzide and Cyclophosphamide, by gender? *:

female:

  1. Hypokalaemia (low potassium)
  2. Dehydration (dryness resulting from the removal of water)
  3. Dizziness
  4. Fatigue (feeling of tiredness)
  5. Leukocytosis (increased white blood cells)
  6. Nausea (feeling of having an urge to vomit)
  7. Pyrexia (fever)
  8. Urinary tract infection
  9. Abdominal pain
  10. Atelectasis (partial or complete collapse of the lung)

male:

  1. Bone disorder
  2. Enterococcal sepsis
  3. Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Toxic neuropathy (nerve damage caused by toxic (harmful) substances)
  6. Fatigue (feeling of tiredness)
  7. Limb discomfort (discomfort in leg)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Oesophagitis (inflammation of oesophagus)
  10. Pain

What are the common drug interactions of Maxzide and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Leukocytosis (increased white blood cells)
  2. Pyrexia (fever)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Adrenal disorder
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Chills (felling of cold)
  8. Cough
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea

50-59:

  1. Abdominal pain
  2. Colitis (inflammation of colon)
  3. Diarrhoea haemorrhagic (bloody diarrhoea)
  4. Haemorrhage (bleeding)
  5. Loose stools
  6. Necrosis (the death of body tissue)

60+:

  1. Hypokalaemia (low potassium)
  2. Urinary tract infection
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chest pain
  5. Dizziness
  6. Electrocardiogram abnormal
  7. Emotional distress
  8. Escherichia infection (bacterial infection by escherichia coli)
  9. Escherichia test positive
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Breast Cancer: 5 people, 27.78%
  2. Nausea (feeling of having an urge to vomit): 3 people, 16.67%
  3. Sinusitis (inflammation of sinus): 3 people, 16.67%
  4. Stress And Anxiety: 2 people, 11.11%
  5. Depression: 2 people, 11.11%
  6. Amyloidosis (a tumour within which amyloid is produced): 2 people, 11.11%
  7. Pain: 2 people, 11.11%
  8. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 5.56%
  9. Muscle Spasms (muscle contraction): 1 person, 5.56%
  10. Muscle Aches (muscle pain): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Maxzide and Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxzide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene and cyclophosphamide (the active ingredients of Maxzide and Cyclophosphamide, respectively), and Maxzide and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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