Maxzide and Lipoic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Lipoic acid (alpha - lipoic acid). Common drug interactions include carpal tunnel syndrome among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Lipoic acid. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Lipoic acid?

Lipoic acid has active ingredients of alpha - lipoic acid. It is often used in peripheral neuropathy. eHealthMe is studying from 5,920 Lipoic acid users. Check the latest studies of Lipoic acid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

18 people who take Maxzide and Lipoic acid together, and have interactions are studied.

Maxzide and Lipoic acid drug interactions.

What are the common drug interactions of Maxzide and Lipoic Acid, by gender? *:

female:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Drug ineffective
Inflammation
Oesophageal spasm (contraction of oesophagus)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug tolerance decreased
Hip arthroplasty
Restless legs syndrome (a powerful urge to move your legs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

Back pain
Chest pain
Heart rate increased
Neck pain

What are the common drug interactions of Maxzide and Lipoic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Back pain
Chest pain
Heart rate increased
Neck pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Drug ineffective
Drug tolerance decreased
Oesophageal spasm (contraction of oesophagus)

60+:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Drug ineffective
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 72.22%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 72.22%
Stress And Anxiety: 2 people, 11.11%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 5.56%
Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 1 person, 5.56%
Diabetes: 1 person, 5.56%
Dry Eyes (lack of adequate tears): 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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