Maxzide and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Zoledronic (zoledronic acid). Common drug interactions include anxiety among females and blister among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Zoledronic. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

On Jul, 15, 2026

11 people who take Maxzide and Zoledronic together, and have interactions are studied.

Maxzide and Zoledronic drug interactions.

What are the common drug interactions of Maxzide and Zoledronic, by gender? *:

female:

Anxiety
Constipation
Metastases to bone (cancer spreads to bone)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ascites (accumulation of fluid in the abdominal cavity)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Breast cancer
Breast cancer metastatic
Colitis (inflammation of colon)
Decreased activity

male:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cataract (clouding of the lens inside the eye)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Skin ulcer
Stomatitis (inflammation of mucous membrane of mouth)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Maxzide and Zoledronic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Breast cancer
Depression
Fatigue (feeling of tiredness)
Metastases to bone (cancer spreads to bone)
Metastases to spine (cancer spreads to spine)
Panic attack
Peripheral swelling

50-59:

n/a

60+:

Constipation
Anxiety
Metastases to peritoneum (cancer spreads to peritoneum)
Pleural effusion (water on the lungs)
Pneumonia
Vocal cord paralysis
Abdominal discomfort
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Blood urea increased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
Metastases To Bone (cancer spreads to bone): 3 people, 27.27%
Pain: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Gastritis (inflammation of stomach): 2 people, 18.18%
Breast Cancer: 2 people, 18.18%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 18.18%
Constipation: 2 people, 18.18%
Dyspnea (difficult or laboured breathing): 2 people, 18.18%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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