Mayzent and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mayzent (siponimod fumaric acid) and Advil (ibuprofen). Common drug interactions include heart rate decreased among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Mayzent and Advil. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Mayzent?

Mayzent has active ingredients of siponimod fumaric acid. eHealthMe is studying from 10,269 Mayzent users. Check the latest studies of Mayzent.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

On Aug, 01, 2026

31 people who take Mayzent and Advil together, and have interactions are studied.

What are the common drug interactions of Mayzent and Advil, by gender? *:

female:

Heart rate decreased
Vertigo
Arthralgia (joint pain)
Back pain
Drug ineffective
Depression
Hypoaesthesia (reduced sense of touch or sensation)
Muscular weakness (muscle weakness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Dyspnoea (difficult or laboured respiration)

male:

Balance disorder
Gait disturbance
Peroneal nerve palsy
Quality of life decreased
Arthralgia (joint pain)

What are the common drug interactions of Mayzent and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Coronavirus test positive
Memory impairment
White blood cell count decreased
Fall

50-59:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Constipation
Drug ineffective
Gait disturbance
Intervertebral disc degeneration (spinal disc degeneration)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Fall
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)

60+:

Dizziness
Heart rate decreased
Vertigo
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Visual impairment

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 22 people, 70.97%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 9.68%
Insomnia (sleeplessness): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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