Mayzent and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mayzent (siponimod fumaric acid) and Melatonin (melatonin). Common drug interactions include dizziness among females and mood altered among males.

The phase IV clinical study analyzes what interactions people have when they take Mayzent and Melatonin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Mayzent?

Mayzent has active ingredients of siponimod fumaric acid. eHealthMe is studying from 10,269 Mayzent users. Check the latest studies of Mayzent.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 30, 2026

33 people who take Mayzent and Melatonin together, and have interactions are studied.

Mayzent and Melatonin drug interactions.

What are the common drug interactions of Mayzent and Melatonin, by gender? *:

female:

Dizziness
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Fall
Hallucination (an experience involving the perception of something not present)
Abdominal pain upper
Energy increased
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Mood altered (changes in mood)
Apathy
Total lung capacity decreased
Adverse reaction
Arthralgia (joint pain)
Asthenia (weakness)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Dyspnoea (difficult or laboured respiration)
Liver disorder (liver diseases)

What are the common drug interactions of Mayzent and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Headache (pain in head)

30-39:

Pyelonephritis (inflammation of kidney caused by bacteria)
Respiratory distress (difficulty in breathing)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

Agitation (state of anxiety or nervous excitement)
Drug ineffective
Hallucination (an experience involving the perception of something not present)
Poor quality sleep
Restlessness (not able to rest)

50-59:

Dizziness
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Back pain
Balance disorder

60+:

Dizziness
Energy increased
Fall
Spinal fracture (fracture in one of vertebrae)
Hallucination (an experience involving the perception of something not present)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 24 people, 72.73%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 15.15%
Depression: 5 people, 15.15%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 3 people, 9.09%
Rickets (softening of bones): 3 people, 9.09%
Pain In Extremity: 3 people, 9.09%
Nausea (feeling of having an urge to vomit): 3 people, 9.09%
Muscle Spasms (muscle contraction): 3 people, 9.09%
Clinically Isolated Syndrome (individual's first neurological episode, caused by inflammation or demyelination of nerve tissue): 3 people, 9.09%
Weight Decreased: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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